(1) Thomas Jefferson vs. (5) Marie Curie

The Breakdown

Curie keeps rolling through this tournament after her second-round upset of Aristotle. Does the two-time Nobel winner have what it takes to take down the man who bought Louisiana and sent Lewis and Clark out on their famous expedition? Curie coined the word "radioactivity," while Jefferson can claim the Earth-shattering "When in the Course of human events it becomes necessary for one people to dissolve the political bands which have connected them with another"¦" that kicks off the Declaration of Independence. Jefferson may have been the greatest American president, but Curie was the first woman ever to have her ashes enshrined at Paris' Pantheon on the strength of her own work. Both of these candidates are scholars for the ages, but which one's the bigger genius?

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[See the whole bracket here.]