Scientists Accidentally Discover Ancient Hepatitis B in a 16th-Century Mummy

Gino Fornaciari, University Of Pisa
Gino Fornaciari, University Of Pisa

Since the 1980s, a child mummy buried in the Basilica of Saint Domenico Maggiore in Naples, Italy in the 16th century has been known as the earliest recorded case of smallpox in the world. The problem is, the 2-year-old didn’t have smallpox, according to new research spotted by IFLScience. But, as the scientists reexamining the remains discovered, it’s still a landmark study in disease evolution. It appears to be the earliest instance of hepatitis B that researchers have ever found in Italy, giving scientists insight into how the virus has evolved over the last several centuries.

The hepatitis B virus (HBV) attacks the liver and can result in cirrhosis and liver cancer, killing around 887,000 people per year. Though it can now be largely prevented by a vaccine, the World Health Organization estimates that 257 million people around the world live with HBV. It often affects children, spreading from mother to child during birth.

For the current study published in PLOS Pathogens, a team of researchers from McMaster University in Canada set about studying the child mummy with the hopes of continuing their past work nailing down how smallpox spread and evolved over human history. But when they used molecular analysis to study the mummy’s skin and bones, they didn’t find anything that indicated that the toddler had smallpox. Instead, they found the hepatitis B virus—which can cause a rash called Gianotti-Crosti Syndrome that the original researchers studying the mummy may have mistaken for the telltale rash associated with smallpox.

The ancient HBV strain found in the mummy's tissues had a genome closely related to that of the modern virus, which, The New York Times explains, could very well mean that the mummy was contaminated when it was first studied in the 1980s. But after analyzing the genetic material further and studying other examples of older HBV strains, they found that it’s plausible that the virus just hasn’t evolved extensively in the past 500 years. Though the contamination theory is still possible, it’s more likely that the mummy really does carry an ancient version of the virus. Considering that HBV has also been traced back to the 16th century in Asia, it’s likely that Europeans were suffering from it around the same time.

[h/t IFLScience]

Amazon's Best Cyber Monday Deals on Tablets, Wireless Headphones, Kitchen Appliances, and More

Amazon
Amazon

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Archaeologists Discover the Jousting Yard Where Henry VIII Had His Historic Accident

National Trust, Wikimedia Commons // Public Domain
National Trust, Wikimedia Commons // Public Domain

Henry VIII may have never earned his reputation as an ill-mannered tyrant if it weren't for injuries he sustained at age 44. Now, as Live Science reports, archaeologists have uncovered the infamous jousting yard where that history-changing accident took place.

Prior to the beheading of Anne Boleyn—his second of six wives—King Henry VIII was regarded as a kind, gregarious leader by those who knew him. The point where descriptions of him changed their tone coincided with a fall he took on January 24, 1536.

While jousting at Greenwich Palace, Henry was tossed from his armored horse and further injured when his steed fell on top of him. The incident caused him to lose consciousness for two hours and nearly cost him his life.

Though it was never diagnosed, some experts believe Henry VIII sustained a brain injury that day that altered his personality. From that point on, he was characterized as irritable and cruel. He was in constant pain from migraines and an ulcerated leg, which could also explain the mood shift. The (sometimes violent) dissolution of most of his marriages occurred post-accident.

Ruins of the jousting yard, or tiltyard, where that fateful incident took place are located 5.5 feet beneath the Maritime Greenwich World Heritage Site, the former site of Greenwich Palace. After falling into disrepair, the palace was demolished by Charles II, and the exact location of the tiltyard was forgotten. A team of archaeologists led by Simon Withers of the University of Greenwich used ground-penetrating radar (GPR) to locate the remnants buried beneath the ground earlier this year.

The giveaways were the footprints of two octagonal towers. The archaeologists say these were likely the foundations of the bleacher-like viewing stands where spectators watched jousting matches. That would place the historic tiltyard about 330 feet east of where it was originally thought to be situated.

The radar scans provided a peek at what lies beneath the Maritime Greenwich World Heritage Site, but to learn more, the archaeologists will need to get their hands dirty. Their next step will be digging up the site to get a better look at the ruins.

[h/t Live Science]