The First Shot to Stop Chronic Migraines Just Secured FDA Approval

iStock
iStock

Migraine sufferers unhappy with current treatments will soon have a new option to consider. Aimovig, a monthly shot, just received approval from the Food and Drug Administration and is now eligible for sale, CBS News reports. The shot is the first FDA-approved drug of its kind designed to stop migraines before they start and prevent them over the long term.

As Mental Floss reported back in February before the drug was cleared, the new therapy is designed to tackle a key component of migraine pain. Past studies have shown that levels of a protein called calcitonin gene–related peptide (CGRP) spike in chronic sufferers when they're experiencing the splitting headaches. In clinical trials, patients injected with the CGRP-blocking medicine in Aimovig saw their monthly migraine episodes cut in half (from eight a month to just four). Some subjects reported no migraines at all in the month after receiving the shot.

Researchers have only recently begun to untangle the mysteries of chronic migraine treatment. Until this point, some of the best options patients had were medications that weren't even developed to treat the condition, like antidepressants, epilepsy drugs, and Botox. In addition to yielding spotty results, many of these treatments also come with severe side effects. The most serious side effects observed in the Aimovig studies were colds and respiratory infections.

Monthly Aimovig shots will cost $6900 a year without insurance. Now that the drug has been approved, a flood of competitors will likely follow: This year alone, three similar shots are expected to receive FDA clearance.

[h/t CBS News]

The ChopBox Smart Cutting Board Has a Food Scale, Timer, and Knife Sharper Built Right Into It

ChopBox
ChopBox

When it comes to furnishing your kitchen with all of the appliances necessary to cook night in and night out, you’ll probably find yourself running out of counter space in a hurry. The ChopBox, which is available on Indiegogo and dubs itself “The World’s First Smart Cutting Board,” looks to fix that by cramming a bunch of kitchen necessities right into one cutting board.

In addition to giving you a knife-resistant bamboo surface to slice and dice on, the ChopBox features a built-in digital scale that weighs up to 6.6 pounds of food, a nine-hour kitchen timer, and two knife sharpeners. It also sports a groove on its surface to catch any liquid runoff that may be produced by the food and has a second pull-out cutting board that doubles as a serving tray.

There’s a 254nm UVC light featured on the board, which the company says “is guaranteed to kill 99.99% of germs and bacteria" after a minute of exposure. If you’re more of a traditionalist when it comes to cleanliness, the ChopBox is completely waterproof (but not dishwasher-safe) so you can wash and scrub to your heart’s content without worry. 

According to the company, a single one-hour charge will give you 30 days of battery life, and can be recharged through a Micro USB port.

The ChopBox reached its $10,000 crowdfunding goal just 10 minutes after launching its campaign, but you can still contribute at different tiers. Once it’s officially released, the ChopBox will retail for $200, but you can get one for $100 if you pledge now. You can purchase the ChopBox on Indiegogo here.

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The Right Way to Clean Your Face Mask

Properly cleaning your face mask is important to keep it free of infectious material.
Properly cleaning your face mask is important to keep it free of infectious material.
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In an effort to slow the transmission of coronavirus in public settings, health officials are advising that people unable to practice social distancing wear a cloth face mask. While not as effective at filtering respiratory droplets as medical-grade masks, cloth masks are still recommended as a practical preventative step.

Like all apparel, masks get dirty. They absorb sweat and germs, and they need to be cleaned. But how?

According to National Geographic, the best way to clean a cloth face mask is to take the same approach as the rest of your laundry—toss it in the washer. Laundry detergent is effective against coronavirus because the pathogen is encased in a layer of oily lipids and proteins. Detergents and hand soaps contain surfactants, which reduce the surface tension of the fatty layer. The surfactant molecule is attracted to oil and grease on one end and water on the other. The end that disrupts the oil bursts the coronavirus envelope apart. Tiny pods of surfactant called micelles trap and wash the remnants away. It’s this activity, not the water temperature, that kills the virus, though using a higher dryer temperature can destroy most microorganisms that might be lingering.

Bear in mind there’s a recommended way to take off your mask. Make sure your hands are clean, then pull it off using the straps behind your ears. This avoids contaminating the mask—and your face—with any pathogens that might be on your hands.

Medical-grade masks are trickier, as they’re intended to be used only once and can’t stand up to a wash cycle. If you have an N95 or paper mask, you can set it aside for several days, at which point the virus is likely to become inactive. But keep in mind that health officials still aren’t entirely sure how long coronavirus can persist on surfaces, and it’s possible for a mask to collect particles over time, increasing the viral load.

But what about the rest of your clothes? Experts say not to worry so much about disrobing the minute you get home. The coronavirus likes moisture and dries out quickly on fabrics. You need to be careful with the material covering your face, but the rest of your outfit can wait until your regularly scheduled laundry appointment.

[h/t National Geographic]