Science Explains Why Your Lab Is Always Hungry

iStock
iStock

Dogs love food. Some love it more than others, and some of those are Labrador retrievers—the bottomless pits of the canine world. Scientists announced today that they’ve found a gene variant in labs that may explain that constant state of "Please Feed Me." The findings were published last year in the journal Cell Metabolism.

Dog obesity isn't something we talk about a lot, but there sure is a lot of it. In the U.S. and other wealthy countries, between 34 and 59 percent of dogs are overweight. And yes, fat dogs are cute, but they’re also in danger of some serious health problems. Canine obesity can cause heart disease, strain on a dog’s joints, diabetes, and can even shorten a dog’s lifespan.

Some breeds, like black labs, chocolate labs, and golden retrievers, are more obesity-prone than others. This is likely because, like many of us, they are highly motivated by food. Labs’ human companions learn quickly that a treat is the trick to getting their dog to behave. But those treats add up.

The domesticated dog, Canis familiaris, is a single species with a lot of variations. Great Danes and Chihuahuas are both dogs, but their bloodlines, and therefore their genes, are dramatically different. And all those differences within a single species make dog breeds a great resource for scientists studying genetics.

Researchers recruited nearly 400 adult Labrador participants. Of those dogs, 310 were pets recruited through an email invitation from the UK Kennel Club, and 80 were part of an assistance-dog breeding colony. Some of the dogs were fat, while others were not, but all of them were healthy, with no pre-existing conditions.

First, the dogs were weighed. Then the scientists collected drool samples from 33 of the dogs and sequenced the DNA within. The dogs’ owners then completed a survey about their labs’ eating habits.

As relatives, of course, the labs had a great deal of genetic material in common with each other and with other dog breeds. But they also had one gene variant that stood out: the deletion of 14 base pairs from a gene called pro-opiomelanocortin, or POMC. Previous studies of this POMC variant have shown a relationship with appetite and a feeling of fullness.

Each dog could have one copy of the POMC variant, two copies, or none. The more copies a dog had, the fatter and more food-motivated it was. And about 23 percent of labs are carrying at least one copy of the variant.

"People who live with Labradors often say they are obsessed by food, and that would fit with what we know about this genetic change," Cambridge University metabolism expert and lead author Eleanor Raffan said in a press statement.

Her co-author, Stephen O’Rahilly of the Wellcome Trust-Medical Research Council Institute of Science, says these findings have implications beyond kibble. "Common genetic variants affecting the POMC gene are associated with human body weight and there are even some rare obese people who lack a very similar part of the POMC gene to the one that is missing in the dogs. So further research in these obese Labradors may not only help the well-being of companion animals but also have important lessons for human health."

Amazon's Under-the-Radar Coupon Page Features Deals on Home Goods, Electronics, and Groceries

Stock Catalog, Flickr // CC BY 2.0
Stock Catalog, Flickr // CC BY 2.0

This article contains affiliate links to products selected by our editors. Mental Floss may receive a commission for purchases made through these links.

Now that Prime Day is over, and with Black Friday and Cyber Monday still a few weeks away, online deals may seem harder to come by. And while it can be a hassle to scour the internet for promo codes, buy-one-get-one deals, and flash sales, Amazon actually has an extensive coupon page you might not know about that features deals to look through every day.

As pointed out by People, the coupon page breaks deals down by categories, like electronics, home & kitchen, and groceries (the coupons even work with SNAP benefits). Since most of the deals revolve around the essentials, it's easy to stock up on items like Cottonelle toilet paper, Tide Pods, Cascade dishwasher detergent, and a 50 pack of surgical masks whenever you're running low.

But the low prices don't just stop at necessities. If you’re looking for the best deal on headphones, all you have to do is go to the electronics coupon page and it will bring up a deal on these COWIN E7 PRO noise-canceling headphones, which are now $80, thanks to a $10 coupon you could have missed.

Alternatively, if you are looking for deals on specific brands, you can search for their coupons from the page. So if you've had your eye on the Homall S-Racer gaming chair, you’ll find there's currently a coupon that saves you 5 percent, thanks to a simple search.

To discover all the deals you have been missing out on, head over to the Amazon Coupons page.

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Treat Your Feline This Holiday Season With Fancy Feast’s Cat Food Advent Calendar

Fancy Feast/Chewy
Fancy Feast/Chewy

In anticipation of the holiday season, many children and adults get to unwrap mini presents each of the 24 days leading up to Christmas day, during what's known as Advent. Though Advent itself dates back to the 4th century, the version we know today, complete with the chocolate-filled calendars, was popularized in the early 1900s. And apparently it's no longer just for humans, because Fancy Feast is letting your feline roommate in on the fun with this unique cat food Advent calendar, now available at Chewy for $23.

For the 24 days leading up to Christmas, your cat will get to enjoy a variety of different wet foods, including favorites like grilled salmon, chicken, and more. There is even a unique ornament included with each calendar featuring a cat in the shape of a heart that can go right onto your tree. (Also, don't be surprised to find your actual cat making its way into the middle of your tree; they're known climbers.)

Now while you enjoy your Advent calendars from brands like LEGO, Funko, and more, your cat will be able to join in on the fun as well. To learn more about Fancy Feast's Feastivites Advent Calendar, head on over to Chewy.

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