Scientists Put a GIF Inside Living Bacteria

Researchers at Harvard University have figured out a way to embed moving images into the DNA of E. coli bacteria. The team described their process in the journal Nature.

It's a setup any spy would love: a code within a code. The paper authors see bacterial DNA as a form of information storage, almost like a computer's hard drive. As the science of gene editing technology advances, we're learning how to fit more—and more complex—information on the same equipment.

Enabling this advancement is a gene editing technique called CRISPR-Cas, which gives scientists access to certain immune-activating regions of bacterial DNA. Researchers have already used that access to engineer malaria-resistant mosquitoes and track down disease-causing pathogens. 

Other scientists have successfully inserted secret messages in E. coli's genetic blueprints. Some have even gotten the bacteria to hold pictures. But until now, none of those pictures have moved.

The Harvard team wanted to see how far CRISPR-Cas could get them. First, they had to select their images. And while some researchers may have taken this opportunity to immortalize a goofy cat GIF, the Harvard team wanted the content of the first-ever bacterial home movies to have significance.

Eadweard Muybridge was a 19th-century photographer whose work blurred the line between art and science. Muybridge pushed the camera technology of the time to its limits, using what was then high-speed imaging to capture incredible shots of people and other animals in motion. His photos showed us the potential of both cameras and our bodies.

And so the authors of the new paper thought it would be appropriate to make their first moving image a Muybridge—specifically, his groundbreaking image of a horse in full gallop. They converted the images to pixels, then converted those pixels to nucleotides, which are often called the building blocks of DNA. They popped those nucleotides into the bacteria's genetic code, then ran the DNA through a sequencer to see if the pixel information stayed in place. It did.

But lead author Seth Shipman says printing images is just the beginning. He envisions a world in which our cells work like microscopic cameras, recording the state and goings-on inside our bodies.

"What we want this system to be used for, eventually, is not to encode information that we already have, but for a way for cells to go out and gather information that we don't have access to," Shipman told Popular Science. "If we could have them collect data and then store that data in their genomes, then we might have access to completely new types of information."

If that concept sounds kind of creepy to you, we have some good news: It's still a long way off.

[h/t Popular Science]

Amazon's Under-the-Radar Coupon Page Features Deals on Home Goods, Electronics, and Groceries

Stock Catalog, Flickr // CC BY 2.0
Stock Catalog, Flickr // CC BY 2.0

This article contains affiliate links to products selected by our editors. Mental Floss may receive a commission for purchases made through these links.

Now that Prime Day is over, and with Black Friday and Cyber Monday still a few weeks away, online deals may seem harder to come by. And while it can be a hassle to scour the internet for promo codes, buy-one-get-one deals, and flash sales, Amazon actually has an extensive coupon page you might not know about that features deals to look through every day.

As pointed out by People, the coupon page breaks deals down by categories, like electronics, home & kitchen, and groceries (the coupons even work with SNAP benefits). Since most of the deals revolve around the essentials, it's easy to stock up on items like Cottonelle toilet paper, Tide Pods, Cascade dishwasher detergent, and a 50 pack of surgical masks whenever you're running low.

But the low prices don't just stop at necessities. If you’re looking for the best deal on headphones, all you have to do is go to the electronics coupon page and it will bring up a deal on these COWIN E7 PRO noise-canceling headphones, which are now $80, thanks to a $10 coupon you could have missed.

Alternatively, if you are looking for deals on specific brands, you can search for their coupons from the page. So if you've had your eye on the Homall S-Racer gaming chair, you’ll find there's currently a coupon that saves you 5 percent, thanks to a simple search.

To discover all the deals you have been missing out on, head over to the Amazon Coupons page.

Sign Up Today: Get exclusive deals, product news, reviews, and more with the Mental Floss Smart Shopping newsletter!

Late MythBusters Star Grant Imahara Honored With New STEAM Foundation

Grant Imahara attends San Diego Comic-Con
Grant Imahara attends San Diego Comic-Con
Genevieve via Flickr // CC BY 2.0

Fans of MythBusters and White Rabbit Project host Grant Imahara were saddened to hear of his passing due to a brain aneurysm in July 2020 at the age of 49. Imahara, a graduate of the University of Southern California, used the television medium to share his love of science and engineering. Now, his passion for education will continue via an educational foundation developed in his name.

The Grant Imahara STEAM Foundation was announced Thursday, October 23, 2020 by family and friends on what would have been Imahara’s 50th birthday. The Foundation will provide mentorships, grants, and scholarships that will allow students from diverse backgrounds access to STEAM education, which places an emphasis on science, technology, engineering, arts, and math. (Formerly referred to as STEM, the “A” for art was added more recently.)

Imahara had a history of aiding students. While working at Industrial Light and Magic in the early 2000s, he mentored the robotics team at Richmond High School to prepare for the international FIRST Robotics Competition. Whether he was working on television or behind-the-scenes on movies like the Star Wars prequels and The Matrix sequels, Imahara always found time to promote and encourage young engineering talent.

The Grant Imahara STEAM Foundation’s founding board members include Imahara’s mother, Carolyn Imahara, and close friends Don Bies, Anna Bies, Edward Chin, Fon H. Davis, Coya Elliott, and Ioanna Stergiades.

“There are many students, like my son Grant, who need the balance of the technical and the creative, and this is what STEAM is all about,” Carolyn Imahara said in a statement. “I’m so proud of my son’s career, but I’m equally proud of the work he did mentoring students. He would be thrilled that we plan to continue this, plus much more, through The Grant Imahara STEAM Foundation.”

Imahara friend Wade Bick is also launching an effort in concert with the USC Viterbi School of Engineering to name a study lounge after Imahara. Donations can be made here.

You can find out more about the foundation, and make a donation, on its website.