The Real Reason the Lyme Disease Vaccine Had No Shot

iStock
iStock

With the potential for causing a variety of lingering symptoms ranging from lethargy to nervous system damage, Lyme disease has become a perennial concern for people venturing outdoors in the summer months. Carried by deer ticks, the Borrelia burgdorferi bacteria can challenge our immune systems and prove frustrating to treat. About 30,000 cases are reported to the CDC each year, although the total cases of unreported transmissions could be ten times that number.

So why don’t we have a vaccine for it? We did. And it disappeared.

According to Vox, the spread of Lyme cases in the 1990s compelled pharmaceutical company GlaxoSmithKline to research and develop a vaccine called LYMErix that attacked the outer protein present in the bacteria. It did so by becoming proactively aggressive, killing off the bacteria while it was still in the body of the attached and feeding tick. More than 1.5 million people were given the vaccine before 2000. Clinical trials demonstrated up to a 90 percent success rate.

While that kind of efficacy and protection would be welcome today, at the time doctors weren’t quite certain what kind of demographic they should be recommending the vaccine to: There was less information about regional areas of tick concentrations than there is now. The vaccine also required three doses in the span of a year, making it slightly inconvenient; some health insurers resisted the $50 cost for each injection.

Those issues were surmountable over time. But some members of the Food and Drug Administration (FDA) panel that had approved the vaccine voiced concern that LYMErix might potentially attack healthy proteins in the body. This autoimmune reaction was never demonstrated in trials, but the theory made consumers wary when it was publicized in the media, and some of those treated complained of arthritis symptoms. Coupled with increasing scrutiny and apprehension over vaccines in general, LYMErix failed to become a staple of vaccination schedules. Sales dropped and GlaxoSmithKline stopped production. With the patent having expired, it’s not likely drug companies will be interested in resurrecting it, only to face additional bad press. Alternative vaccines are being considered, but could take years before coming to market.

In the absence of an effective vaccine, the best way to ward off Lyme remains prevention. If you’re going to be in wooded areas where the ticks tend to congregate, wearing light-colored clothing will help you spot the small nymphs. Insect repellent is important, and examining your body—particularly behind the ears and armpits—for ticks after being outside is also a must. If you find one, remove it with a pair of tweezers.

For more information about Lyme disease, check out our 15 Useful Facts.

[h/t Vox]

This Course Will Teach You How to Play Guitar Like a Pro for $29

BartekSzewczyk/iStock via Getty Images
BartekSzewczyk/iStock via Getty Images

Be honest: You’ve watched a YouTube video or two in an attempt to learn how to play a song on the guitar. Whether it was through tabs or simply copying whatever you saw on the screen, the fun always ends when friends start throwing out requests for songs you have no idea how to play. So how about you actually learn how to play guitar for real this time?

It’s now possible to learn guitar from home with the Ultimate Beginner to Expert Guitar Lessons Bundle, which is currently on sale for $29. Grab that Gibson, Fender, or whatever you have handy, and learn to strum rhythms from scratch.

The strumming course will teach you how to count beats and rests to turn your hands and fingers into the perfect accompaniment for your own voice or other musicians. Then, you can take things a step further and learn advanced jamming and soloing to riff anytime, anywhere. This course will teach you to improvise across various chords and progressions so you can jump into any jam with something original. You’ll also have the chance to dive deep into the major guitar genres of bluegrass, blues, and jazz. Lessons in jam etiquette, genre history, and how to read music will separate you from a novice player.

This bundle also includes courses in ear training so you can properly identify any relative note, interval, or pitch. That way, you can play along with any song when it comes on, or even understand how to modify it into the key you’d prefer. And when the time comes to perform, be prepared with skilled hammer-ons, pull-offs, slides, bends, trills, vibrato, and fret-tapping. Not only will you learn the basic foundations of guitar, you’ll ultimately be able to develop your own style with the help of these lessons.

The Ultimate Beginner to Expert Guitar Lessons Bundle is discounted for a limited time. Act on this $29 offer now to work on those fingertip calluses and play like a pro.

 

The Ultimate Beginner to Expert Guitar Lessons Bundle - $29

See Deal


At Mental Floss, we only write about the products we love and want to share with our readers, so all products are chosen independently by our editors. Mental Floss has affiliate relationships with certain retailers and may receive a percentage of any sale made from the links on this page. Prices and availability are accurate as of the time of publication.

The Right Way to Clean Your Face Mask

Properly cleaning your face mask is important to keep it free of infectious material.
Properly cleaning your face mask is important to keep it free of infectious material.
mikography/iStock via Getty Images

In an effort to slow the transmission of coronavirus in public settings, health officials are advising that people unable to practice social distancing wear a cloth face mask. While not as effective at filtering respiratory droplets as medical-grade masks, cloth masks are still recommended as a practical preventative step.

Like all apparel, masks get dirty. They absorb sweat and germs, and they need to be cleaned. But how?

According to National Geographic, the best way to clean a cloth face mask is to take the same approach as the rest of your laundry—toss it in the washer. Laundry detergent is effective against coronavirus because the pathogen is encased in a layer of oily lipids and proteins. Detergents and hand soaps contain surfactants, which reduce the surface tension of the fatty layer. The surfactant molecule is attracted to oil and grease on one end and water on the other. The end that disrupts the oil bursts the coronavirus envelope apart. Tiny pods of surfactant called micelles trap and wash the remnants away. It’s this activity, not the water temperature, that kills the virus, though using a higher dryer temperature can destroy most microorganisms that might be lingering.

Bear in mind there’s a recommended way to take off your mask. Make sure your hands are clean, then pull it off using the straps behind your ears. This avoids contaminating the mask—and your face—with any pathogens that might be on your hands.

Medical-grade masks are trickier, as they’re intended to be used only once and can’t stand up to a wash cycle. If you have an N95 or paper mask, you can set it aside for several days, at which point the virus is likely to become inactive. But keep in mind that health officials still aren’t entirely sure how long coronavirus can persist on surfaces, and it’s possible for a mask to collect particles over time, increasing the viral load.

But what about the rest of your clothes? Experts say not to worry so much about disrobing the minute you get home. The coronavirus likes moisture and dries out quickly on fabrics. You need to be careful with the material covering your face, but the rest of your outfit can wait until your regularly scheduled laundry appointment.

[h/t National Geographic]