15 Useful Facts About Lyme Disease

Stringer/Getty Images
Stringer/Getty Images

As summer nears and you spend more time outdoors in one of the many beautiful natural spots in the United States, be sure to dress for the season—tick season, that is. Some experts say 2017 may be an especially tick-infested year. Deer ticks (Ixodes scapularis) carry a bacteria that causes Lyme disease, an infection from a bacterium that coils waiting in their insect bodies. Lyme-carrying deer ticks are especially prevalent in the upper East Coast, the upper Midwest, northern California, and the Oregon coast. While not every tick carries the bacteria that lead to infection—and some carry other pathogens—it’s best to take precautions to prevent bites, and seek medical attention if you have been bitten. The infection can cause long-lasting damage if not treated early. Here are 15 facts you need to know about Lyme disease.

1. LYME DISEASE IS CAUSED BY COILED BACTERIA.

Lyme disease is caused by the bacterium Borrelia burgdorferi, a spirochete, or tightly coiled bacterium that looks like a tiny spring under a microscope. Spirochetes are very simple, slow-replicating bacteria that require a mammalian or avian host to survive. According to Timothy Sellati, chair of the infectious diseases department at Southern Research, a nonprofit research institution in Birmingham, Alabama, “It takes on the order of 18–20 hours for a single spirochete to divide into two.” That’s incredibly slow, compared to other bacteria like E. coli, which can replicate every 20 minutes. Because Borrelia replicates so slowly, and they don’t reach high numbers, “They do not show up easily in a blood test,” Sellati says.

2. TICKS PREFER A LONG MEAL.

Sellati explains that ticks are very different feeders from mosquitoes, which he calls “hit-and-run feeders.” Ticks will feed over a period of three to five days before they become fully engorged. Female ticks generally only take three “blood meals,” he says, in the duration of their lifespan. They take one blood meal after hatching from their egg into the larval stage, another after they molt into their nymphal stage—the stage where they are most likely to bite you—and a final “big meal” in preparation for laying thousands of eggs. Adult male ticks generally don’t feed, he says.

3. THEY ARE A VIRULENT DISEASE VECTOR …

When an infected tick bites a human, the waiting spirochetes—which live essentially dormant in the tick’s gut until environmental cues such as changes in temperature and oxygen availability awaken them—travel from the tick’s gut to its saliva glands. “From the saliva glands they can literally be spat into the bloodstream that the tick is feeding on,” Sellati says. Once they enter the bloodstream, spirochetes travel to various body tissues, because if they stay too long in the bloodstream, they’ll get killed by their host's immune system. “Once it gets away from site of inoculation, it shows a bias toward joints, heart, central nervous system,” Sellati says.

4. … WHICH LEADS TO INFLAMMATION.

“The bacteria has components that are very effective at eliciting an inflammatory response,” Sellati explains. While Borrelia don’t produce toxins like other bacteria, they do incite inflammation in sensitive parts of the body such as the joints, heart, and brain. “That inflammatory response is important to help kill and clear the spirochetes, but it causes collateral damage as well.”

5. INFECTIONS MAY BEGIN WITH A BULL'S-EYE.

The first symptom to look for in about 80 to 90 percent of Lyme cases is a telltale rash of an infected tick bite, called an erythema migrans (EM) rash, which looks a lot like a red bull's-eye, and usually appears at the site of a tick bite within seven to 14 days, according to the American Lyme Disease Foundation. However, the rash does not appear in every instance of Lyme disease, so if you’re bitten, you should visit a doctor immediately. You may also experience flu-like symptoms or joint pains in the first month after the bite.

6. DON'T WAIT TO GET TREATMENT.

If you don't see the tick bite, and don't treat early symptoms, the spirochetes continue to spread throughout your body and can cause more severe symptoms, including fatigue, stiff or aching neck, tingling or numbness in your extremities, and even paralysis of your face. Even more debilitating symptoms of later-stage Lyme disease can include severe headaches, painful arthritis and swelling of joints, cardiac abnormalities, and central nervous system debilitations leading to cognitive disorders.

7. IF CAUGHT EARLY, IT'S USUALLY HIGHLY TREATABLE …

When the disease is caught in its early stages, and treated with antibiotics, it’s curable, Sellati says. Even later stages of the disease can be treated, but the longer an infection goes untreated, the more severe the symptoms and damage can become.

8. … BUT SOME PATIENTS EXPERIENCE SYMPTOMS FOR MUCH LONGER.

Scientists are not entirely sure why a subset of patients have recurrent symptoms of the illness in the months and even years following treatment, known as post-treatment Lyme disease syndrome. “It’s not clear if there is a persistence of live replicating bacteria in some immune privileged niche where they’re protected from exposure to antibiotics,” Sellati says, or if it’s simply the subsequent inflammation stirred up in the body that refuses to go back to normal. “What drives that is not entirely clear.”

9. YOUR GENETICS MAY DICTATE YOUR TREATMENT.

Sellati’s lab has been exploring whether genetics plays a role in who recovers after treatment and who doesn’t. “We have some evidence that your genetic makeup can actually predispose you to developing post-treatment Lyme disease syndrome," Sellati says, and adds it will require more research. They believe they might be able to isolate genetic markers that will tell doctors if antibiotics alone will work, or if the patient might need additional treatment.

10. FEAR THE ENGORGED TICK (BUT DON'T PANIC).

The good news is, even if a tick bites you, if it isn’t yet fully engorged on your blood, chances are good it hasn’t been there long enough to transmit the spirochetes that lead to infection. However, it’s always better to be safe, and pay attention to any symptoms that occur thereafter. “The sooner you can remove a tick from your body, whether it’s feeding or not, the better. If the tick is feeding for less than 24 hours, the likelihood of being infected with Borellia is significantly reduced,” Sellati says.

11. AREAS WITH MICE HAVE MORE LYME DISEASE.

Wherever you find mice and deer you’re very likely to find ticks as well. In fact, Sellati says, mice in all forms—but especially the white-footed mouse—are what infectious researchers call a “maintenance reservoir.” Sellati says. “They maintain the bacteria in the wild so that new ticks can acquire it.” Since spirochetes tend to stay in the bloodstream of mice much longer than they do in humans, that’s how ticks have such an endless supply of the bacteria. “If you got rid of all the mice in the world, you would either come very close to or significantly reduce the population of Borellia in the environment. You’d have a significant decrease in Lyme,” he emphasizes.

12. YOU CAN TAKE SIMPLE STEPS TO PROTECT YOURSELF.

Wear clothes with the most coverage possible. Spray yourself with anti-tick sprays. But no matter what, always do a tick check after you return from the outdoors just to be safe. And if you start to feel any of the symptoms mentioned earlier within a month of a tick bite, don’t wait to visit your doctor.

13. CHECK YOUR CREVICES.

Ticks are not opposed to biting you wherever they can reach, but they have a preference for your warm, moist crevices, such as armpits, backs of the knee, groin, base of the head, and nape of your neck.

14. SKIP SOME OF THOSE "TIPS" FOR REMOVING TICKS THAT YOU'VE HEARD ABOUT.

No matter how many YouTube tutorials you’ve watched, Sellati recommends that you do not use heat, like a match or a lighter, to burn a tick off. The same goes for “goops” such as petroleum jelly, alcohol, or hand sanitizer. Since the spirochetes are transmitted through tick saliva, Sellati warns, “If you try to do those things, you’re only going to piss the tick off, and a pissed-off tick spits a lot, and you're more likely to get more bacteria into your bloodstream.”

15. INSTEAD, USE SLOW, STEADY PRESSURE—AND SOME TWEEZERS.

Take a small pair of forceps or tweezers, Sellati instructs, and gently grasp the tick as close to the skin’s surface as possible, “then pull the tick straight up slowly, which pulls the mouth part out of the skin, and then just dab the area with alcohol to disinfect.” A tick’s mouthparts are like tiny barbed hooks, designed to pierce the skin and stay there. “Then they have secretions that cement the mouthparts to the skin, because they have to feed over a long time and they don’t want to be knocked off while they sit and sip.”

New Cross-Bred Cosmic Crisp Apples Can Stay Fresh for Up to a Year

Cosmic Crisp
Cosmic Crisp

Healthy snackers know only too well the disappointment that comes with biting into what looks like a deliciously crisp apple and getting a mouthful of mealy mush instead. It’s just one of the pome fruit’s many potential issues—they also brown quickly, bruise easily, and don’t last as long as whatever bag of chips you might be tempted to reach for instead.

Enter the Cosmic Crisp, a Washington-grown patented hybrid apple that could be the answer to all your apple-related complaints. According to New Atlas, researchers at Washington State University began breeding the new variety as a cross between Enterprise and Honeycrisp apples in 1997, and it’s officially hitting stores now.

cosmic crisp apple on tree
Cosmic Crisp

Not only does a Cosmic Crisp apple resist bruising and browning better than other kinds of apples, it also boasts an exceptionally long storage life. In a controlled atmosphere, it should stay fresh for a full year—meaning you’ll soon be able to enjoy a crisp, satisfying snack in the middle of March, when out-of-season apples usually leave much to be desired. In your own refrigerator, Cosmic Crisp apples are good for about six months, and they’ll even last for several weeks if you leave them out at room temperature. The long shelf life might cut down on the number of apples that you end up tossing in the trash because they went bad before you got around to eating them.

In a 2012 report published in the American Society for Horticultural Science journal HortScience, the Washington State University researchers found that a group of 114 consumers rated the Cosmic Crisp apple, or WA 38, higher than Fuji apples in sweetness, sourness, flavor intensity, crispness, firmness, juiciness, and overall acceptance. The apple's website even suggests that bakers can reduce the amount of added sugar in recipes that contain Cosmic Crisps.

The Cosmic part of its name comes from the whitish specks on the apple’s skin, which reminded taste testers of a starry sky. In reality, those specks are lenticels—porous openings that allow the apple to exchange gases with its environment.

If you don’t see Cosmic Crisp apples in your grocery store yet, here’s a simple trick for keeping any apples fresh for longer.

[h/t New Atlas]

The Reason So Many Babies Are Conceived in Winter

yurizhuravov/iStock via Getty Images
yurizhuravov/iStock via Getty Images

Does it feel like many friends and family members announce the pending arrival of a baby during the fall and winter months? That’s not exactly a coincidence. It turns out the cold season is associated with more reproductive activity than any other time of the year. The month of December alone accounts for 9 percent of conceptions in the United States. Science is gaining a better understanding of why.

All living creatures heed an evolutionary instinct to target seasonal births. If conception happens during colder months, babies will be born during warmer months, when resources will be bountiful. Northern states have births peaking in June and July, while southern states come a bit later in October and November. The farther south, the later the birth peak, since people in these warm climates are less influenced by frigid temperatures.

What are frisky humans responding to in colder months? Research suggests that the cooler temperatures and shortened days signal that it's time to get busy. Other theories suggest that men may be more fertile in colder months, or that a woman’s ovum receptivity might change with decreased daylight. Not only are couples potentially more sexually active, but that activity might wind up being more (re)productive.

Are there benefits to conceiving at other times? Possibly. One 2013 study published in the Proceedings of the National Academy of Sciences gathered data from nearly 1.5 million births and found that average birth weight in the first five months of the year decreased by 10 grams. Babies born during the summer months were 20 grams heavier. Mothers who conceived in summer tended to gain more weight than those who conceived at other times.

If you have a disproportionate amount of friends with a September birthday, it’s likely that their parents consciously or unconsciously followed their evolutionary instinct nine months earlier.

[h/t Smithsonian]

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