10 Mind-Boggling Psychiatric Treatments

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by Dan Greenberg

Nobody ever claimed a visit to the doctor was a pleasant way to pass the time. But if you're timid about diving onto a psychiatrist's couch or paranoid about popping pills, remember: It could be worse. Like getting-a-hole-drilled-into-your-skull worse.

1. INSULIN COMA-THERAPY

The coma-therapy trend began in 1927. Viennese physician Manfred Sakel accidentally gave one of his diabetic patients an insulin overdose, and it sent her into a coma. But what could have been a major medical faux pas turned into a triumph. The woman, a drug addict, woke up and declared her morphine craving gone. Later, Sakel (who really isn't earning our trust here) made the same mistake with another patient—who also woke up claiming to be cured. Before long, Sakel was intentionally testing the therapy with other patients and reporting a 90 percent recovery rate, particularly among schizophrenics. Strangely, however, Sakel's treatment successes remain a mystery.

Presumably, a big dose of insulin causes blood sugar levels to plummet, which starves the brain of food and sends the patient into a coma. But why this unconscious state would help psychiatric patients is anyone's guess. Regardless, the popularity of insulin therapy faded, mainly because it was dangerous. Slipping into a coma is no walk in the park, and between one and two percent of treated patients died as a result.

2. TREPANATION

Ancient life was not without its hazards. Between wars, drunken duels, and the occasional run-in with an inadequately domesticated pig, it's no surprise that archaic skulls tend to have big holes in them. But not all holes are created with equal abandon. Through the years, archaeologists have uncovered skulls marked by a carefully cut circular gap, which shows signs of being made long before the owner of the head passed away. These fractures were no accident; they were the result of one of the earliest forms of psychiatric treatment called trepanation. The basic theory behind this "therapy" holds that insanity is caused by demons lurking inside the skull. As such, boring a hole into the patient's head creates a door through which the demons can escape, and—voila!—out goes the crazy.

Despite the peculiarity of the theory and lack of major-league anesthetics, trepanation was by no means a limited phenomenon. From the Neolithic era to the early 20th century, cultures all over the world used it as a way to cure patients of their ills. Doctors eventually phased out the practice as less invasive procedures were developed. Average Joes, on the other hand, didn't all follow suit. Trepanation patrons still exist. In fact, they even have their very own organizations, like the International Trepanation Advocacy Group.

3. ROTATIONAL THERAPY

Charles Darwin's grandfather Erasmus Darwin was a physician, philosopher, and scientist, but he wasn't particularly adept at any of the three. Consequently, his ideas weren't always taken seriously. Of course, this could be because he liked to record them in bad poetic verse (sample: "By immutable immortal laws / Impress'd in Nature by the great first cause, / Say, Muse! How rose from elemental strife / Organic forms, and kindled into life"). It could also be because his theories were a bit far-fetched, such as his spinning-couch treatment. Darwin's logic was that sleep could cure disease and that spinning around really fast was a great way to induce the slumber.

Nobody paid much attention to Darwin's idea at first, but later, American physician Benjamin Rush adapted the treatment for psychiatric purposes. He believed that spinning would reduce brain congestion and, in turn, cure mental illness. He was wrong. Instead, Rush just ended up with dizzy patients. These days, rotating chairs are limited to the study of vertigo and space sickness.

4. HYDROTHERAPY

If the word "hydrotherapy" conjures up images of Hollywood stars lazily soaking in rich, scented baths, then you probably weren't an early 20th-century psychiatric patient. Building off the idea that a dip in the water is often calming, psychiatrists of yore attempted to remedy various symptoms with corresponding liquid treatments. For instance, hyperactive patients got warm, tiring baths, while lethargic patients received stimulating sprays.

Some doctors, however, got a bit too zealous about the idea, prescribing therapies that sounded more like punishment than panacea. One treatment involved mummifying the patient in towels soaked in ice-cold water. Another required the patient to remain continuously submerged in a bath for hours or even days—which might not sound so bad, except they were strapped in and only allowed out to use the restroom. Finally, some doctors ordered the use of high-pressure jets. Sources indicate that at least one patient was strapped to the wall in the crucifixion position (never a good sign) and blasted with water from a fire hose. Like many extreme treatments, hydrotherapy was eventually replaced with psychiatric drugs, which tended to be more effective.

5. MESMERISM

Much like Yoda, Austrian physician Franz Mesmer (1734-1815) believed that an invisible force pervaded everything in existence, and that disruptions in this force caused pain and suffering. But Mesmer's ideas would have been of little use to Luke Skywalker. His basic theory was that the gravity of the moon affected the body's fluids in much the same way it caused ocean tides, and that some diseases accordingly waxed and waned with the phases of the moon. The dilemma, then, was to uncover what could be done about gravity's pernicious effects. Mesmer's solution: use magnets. After all, gravity and magnetism were both about objects being attracted to each other. Thus, placing magnets on certain areas of a patient's body might be able to counteract the disruptive influence of the moon's gravity and restore the normal flow of bodily fluids.

Surprisingly, many patients praised the treatment as a miracle cure, but the medical community dismissed it as superstitious hooey and chalked up his treatment successes to the placebo effect. Mesmer and his theories were ultimately discredited, but he still left his mark. Today, he's considered the father of modern hypnosis because of his inadvertent discovery of the power of suggestion, and his name lives on in the English word mesmerize

6. MALARIA THERAPY

Ah, if only we were talking about a therapy for malaria. Instead, this is malaria as therapy—specifically, as a treatment for syphilis. There was no cure for the STD until the early 1900s, when Viennese neurologist Wagner von Jauregg got the idea to treat syphilis sufferers with malaria-infected blood. Predictably, these patients would develop the disease, which would cause an extremely high fever that would kill the syphilis bacteria. Once that happened, they were given the malaria drug quinine, cured, and sent home happy and healthy. The treatment did have its share of side effects—that nasty sustained high fever, for one—but it worked, and it was a whole lot better than dying. In fact, Von Jauregg won the Nobel Prize for malaria therapy, and the treatment remained in use until the development of penicillin came along and gave doctors a better, safer way to cure the STD.

7. CHEMICALLY INDUCED SEIZURES

Nobody ever said doctors had flawless logic. A good example: seizure therapy. Hungarian pathologist Ladislas von Meduna pioneered the idea. He reasoned that, because schizophrenia was rare in epileptics, and because epileptics seemed blissfully happy after seizures, then giving schizophrenics seizures would make them calmer. In order to do this, von Meduna tested numerous seizure-inducing drugs (including such fun candidates as strychnine, caffeine, and absinthe) before settling on metrazol, a chemical that stimulates the circulatory and respiratory systems. And although he claimed the treatment cured the majority of his patients, opponents argued that the method was dangerous and poorly understood.

To this day, no one is quite clear on why seizures can help ease some schizophrenic symptoms, but many scientists believe the convulsions release chemicals otherwise lacking in patients' brains. Ultimately, the side effects (including fractured bones and memory loss) turned away both doctors and patients.

8. PHRENOLOGY

Around the turn of the 19th century, German physician Franz Gall developed phrenology, a practice based on the idea that people's personalities are depicted in the bumps and depressions of their skulls. Basically, Gall believed that the parts of the brain a person used more often would get bigger, like muscles. Consequently, these pumped-up areas would take up more skull space, leaving visible bumps in those places on your head. Gall then tried to determine which parts of the skull corresponded to which traits. For instance, bumps over the ears meant you were destructive; a ridge at the top of the head indicated benevolence; and thick folds on the back of the neck were sure signs of a sexually oriented personality. In the end, phrenologists did little to make their mark in the medical field, as they couldn't treat personality issues, only diagnose them (and inaccurately, at that). By the early 1900s, the fad had waned, and modern neuroscience had garnered dominion over the brain.

9. HYSTERIA THERAPY

Once upon a time, women suffering from pretty much any type of mental illness were lumped together as victims of hysteria. The Greek physician Hippocrates popularized the term, believing hysteria encompassed conditions ranging from nervousness to fainting fits to spontaneous muteness. The root cause, according to him, was a wandering womb. So, whither does it wander? Curious about Hippocrates's theory, Plato asked himself that very question. He claimed that if the uterus "remains unfruitful long beyond its proper time, it gets discontented and angry and wanders in every direction through the body, closes up the passages of the breath, and, by obstructing respiration, drives women to extremity." Consequently, cures for hysteria involved finding a way to "calm down" the uterus. And while there was no dearth of methods for doing this (including holding foul-smelling substances under the patient's nose to drive the uterus away from the chest), Plato believed the only surefire way to solve the problem was to get married and have babies. After all, the uterus always ended up in the right place when it came time to bear a child. Although "womb-calming" as a psychiatric treatment died out long ago, hysteria as a diagnosis hung around until the 20th century, when doctors began identifying conditions such as depression, post-traumatic stress disorder, and phobias.

10. LOBOTOMY

Dr. Walter Freeman, left, and Dr. James W. Watts study an X ray before a psychosurgical operation
Harris A Ewing, Saturday Evening Post, Public Domain, Wikimedia Commons

Everybody's favorite psychiatric treatment, the modern lobotomy was the brainchild of António Egas Moniz, a Portuguese doctor. Moniz believed that mental illnesses were generally caused by problems in the neurons of the frontal lobe, the part of the brain just behind the forehead. So when he heard about a monkey whose violent, feces-throwing urges had been curbed by cuts to the frontal lobe, Moniz was moved to try out the same thing with some of his patients. (The lobe-cutting, not the feces-throwing.) He believed the technique could cure insanity while leaving the rest of the patient's mental function relatively normal, and his (admittedly fuzzy) research seemed to support that. The accolades flooded in, and (in one of the lower points in the Karolinska Institute's history) Moniz was awarded the Nobel Prize in 1949.

After the lobotomy rage hit American shores, Dr. Walter Freeman took to traveling the country in his "lobotomobile" (no, really), performing the technique on everyone from catatonic schizophrenics to disaffected housewives. His road-ready procedure involved inserting a small ice pick into the brain through the eye socket and wiggling it around a bit. While some doctors thought he'd found a way to save hopeless cases from the horrors of life-long institutionalization, others noted that Freeman didn't bother with sterile techniques, had no surgical training whatsoever, and tended to be a bit imprecise when describing his patients' recovery.

As the number of lobotomies increased, a major problem became apparent: The patients weren't just calm—they were virtual zombies who scarcely responded to the world around them. Between that and the bad press lobotomies received in films and novels such as One Flew Over the Cuckoo's Nest, the treatment soon fell out of favor.

Here’s What You Need to Know About the New Coronavirus

jarun011/iStock via Getty Images
jarun011/iStock via Getty Images

This morning, the Centers for Disease Control and Prevention (CDC) confirmed the second case of the recently discovered coronavirus in the U.S. Find out what it is, where it is, how to avoid it, and all the other need-to-know information about the illness below.

What is the new coronavirus?

Coronaviruses are a group of viruses named for the crown-shaped spikes that cover their surfaces (corona is the Latin word for crown). According to the CDC, human coronaviruses can cause upper-respiratory tract illnesses, including the common cold, and can sometimes lead to more severe lower-respiratory tract issues like pneumonia or bronchitis.

Because this latest coronavirus, 2019-nCoV, is so new, health officials are currently trying to figure out how it works and how to treat it. It’s not the first time a potent new coronavirus has caused an international outbreak: SARS-CoV originated in Asia and spread to more than two dozen countries in 2003, and MERS-CoV first infected people in Saudi Arabia before spreading across the globe in 2012.

Where is the coronavirus outbreak happening?

The majority of cases are in China, which counts more than 800 confirmed diagnoses. Most are in Wuhan, a city in China’s Hubei province where 2019-nCoV was first detected last month. Additional cases have been reported in South Korea, Japan, Singapore, Hong Kong, Macao, Taiwan, Thailand, and Vietnam.

The CDC has confirmed two U.S. cases—a man in his thirties outside Seattle, and a 60-year-old woman in Chicago—both of whom had recently returned from trips to Wuhan. A CDC official said another 63 potential cases are being investigated in 22 states, and airports in New York, Chicago, Los Angeles, Atlanta, and San Francisco are conducting health screenings on passengers arriving from China.

Chinese officials have shut down transportation to and from Wuhan. Tourist spots like Beijing’s Forbidden City, Shanghai Disneyland, and a portion of the Great Wall are also closed temporarily.

What are the symptoms of the new coronavirus?

Symptoms are similar to those caused by a cold or the flu, including fever, dry cough, and breathing difficulty. The New York Times reported that as of Friday morning, 25 people in China have died from the virus, and most of them were older men with preexisting health conditions like cirrhosis, diabetes, and Parkinson’s disease.

How does the new coronavirus spread?

Because most of the early cases of 2019-nCoV were traced back to a seafood and meat market in Wuhan, health officials think the virus originally spread from infected animals to humans, but it’s now being transmitted from person to person.

Though scientists are still studying exactly how that happens, the leading theory is that it travels in tiny droplets of fluid from the respiratory tract when a person coughs or sneezes.

How do you avoid the new coronavirus?

The CDC is warning everyone to avoid any nonessential trips to Wuhan, and to avoid animals or sick people if you’re traveling elsewhere in China. If you’ve been to China in the last two weeks and experience any of the symptoms listed above, you should seek medical attention immediately—and you should call the doctor’s office or emergency room beforehand to let them know you’re coming.

Otherwise, simply stick to the precautions you’d normally take when trying to stay healthy: Wash your hands often with soap and water, cover your nose and mouth when coughing or sneezing, stay away from sick people, and thoroughly cook any meat or eggs before eating them.

Should you be worried about the new coronavirus?

The global health community is taking 2019-nCoV seriously in order to curb the outbreak as quickly as possible, but you shouldn’t panic. The CDC maintains that it’s a low-risk situation in the U.S., and public health officials are echoing that message.

“We don’t want the American public to be worried about this, because their risk is low,” Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, told USA Today.

[h/t USA Today]

Has An Element Ever Been Removed From the Periodic Table?

lucadp/iStock via Getty Images
lucadp/iStock via Getty Images

Barry Gehm:

Yes, didymium, or Di. It was discovered by Carl Mosander in 1841, and he named it didymium from the Greek word didymos, meaning twin, because it was almost identical to lanthanum in its properties. In 1879, a French chemist showed that Mosander’s didymium contained samarium as well as an unknown element. In 1885, Carl von Weisbach showed that the unknown element was actually two elements, which he isolated and named praseodidymium and neodidymium (although the di syllable was soon dropped). Ironically, the twin turned out to be twins.

The term didymium filter is still used to refer to welding glasses colored with a mixture of neodymium and praseodymium oxides.

One might cite as other examples various claims to have created/discovered synthetic elements. Probably the best example of this would be masurium (element 43), which a team of German chemists claimed to have discovered in columbium (now known as niobium) ore in 1925. The claim was controversial and other workers could not replicate it, but some literature from the period does list it among the elements.

In 1936, Emilio Segrè and Carlo Perrier isolated element 43 from molybdenum foil that had been used in a cyclotron; they named it technetium. Even the longest-lived isotopes of technetium have a short half-life by geological standards (millions of years) and it has only ever been found naturally in minute traces as a product of spontaneous uranium fission. For this reason, the original claim of discovery (as masurium) is almost universally regarded as erroneous.

As far as I know, in none of these cases with synthetic elements has anyone actually produced a quantity of the element that one could see and weigh that later turned out not to be an element, in contrast to the case with didymium. (In the case of masurium, for instance, the only evidence of its existence was a faint x-ray signal at a specific wavelength.)

This post originally appeared on Quora. Click here to view.

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