Does Drinking Alcohol Kill Brain Cells?

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iStock

Watch someone after they’ve had a few drinks, and you’ll find clear evidence that alcohol does something to their brain. They stumble, slur their words, lose control of their emotions, and forget things. 

Some people have tried to explain this behavior as the aftermath of cell death caused by alcohol. Often, it’s packaged as a neat factoid like “Three beers kill 10,000 brain cells.”

But is this true? No. But alcohol does damage some of your 86 billion brain cells, or neurons, which send electrical and chemical messages within the brain and between it and other parts of the body. 

Ethyl alcohol (the kind found in boozy beverages, also known as ethanol) can kill cells and microorganisms. That’s what makes it an effective antiseptic. Fortunately, when you drink alcoholic beverages, your body tries not to let all of that ethanol roam around unchecked. Enzymes in your liver convert it first info acetaldehyde (which is highly toxic) and then into acetate, which is broken down into water and carbon dioxide and eliminated by your body.

The liver can only work so fast, though, processing about 12 ounces of beer, 5 ounces of wine, or 1.5 ounces of distilled spirits per hour. If you’re knocking drinks back fast enough that your liver can’t keep up, the excess alcohol hangs out in the blood and travels through the body until it can be processed. 

When this alcohol reaches the brain, it doesn’t kill the cells. What it does is inhibit the communication between dendrites, or branching connections at the ends of neurons that send and receive information between neurons, in the cerebellum, a part of the brain involved in motor coordination. This poor communication results in some of the typical impairments of intoxication. 

Researchers at Washington University in St. Louis found that alcohol, even when applied directly to neurons, didn’t kill them. It just interfered with the way they transmit information. Specifically, the researchers showed that alcohol causes certain receptors on neurons to manufacture steroids that inhibit memory formation. 

Some alcoholics can experience neuron death as part of a brain disorder called Wernicke-Korsakoff syndrome. In these cases, the evidence again suggests that the disease and cell death aren’t caused by the alcohol itself, but a B1 (or thiamine) deficiency and general malnutrition that often go hand in hand with alcoholism. 

For moderate drinkers, a number of studies from the last 15 years suggest that, far from killing brain cells, a little tipple is actually associated with a reduced risk of cognitive decline and dementia. 

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Why Do We Celebrate Christmas on December 25?

If Jesus wasn't born on December 25, does this rule still apply?
If Jesus wasn't born on December 25, does this rule still apply?
Jon Tyson, Unsplash

Each December, Christians throw a collective birthday bash to celebrate the anniversary of Jesus’s arrival on Earth. But without a birth certificate—or any other official record of his actual birthdate—in existence, December 25 seems like an arbitrary day for all our Christmas traditions. So how did early observers choose it?

When Was Jesus Really Born?

Since the Bible doesn’t name a month or even a season for Jesus’s birth, historians have relied on other context clues to estimate when it occurred. Shepherds tend sheep in the Nativity story, which people often cite as evidence that Jesus was more likely born during the spring. Others argue that Israel’s mild winter temperatures allow sheep to graze even in December. According to Slate, it’s also possible that sheep set aside for religious sacrifices may have been given free rein, frigid night or not.

The Adoration of the Shepherds by Sebastiano Conca, 1720.J. Paul Getty Museum // Public Domain

One clue pointing specifically to December 25 comes from the story of Mary’s cousin Elizabeth, who approached old age without having given birth to any children. One day, her husband, a priest named Zacharias, was burning incense in the temple when the angel Gabriel appeared to him with good news: Elizabeth would bear a son. Early Christians guessed that Zacharias was probably in the temple for Yom Kippur, which they believed always took place on September 24 (it actually shifts year to year based on the Jewish lunisolar calendar). Nine months after September 24 is June 24, so they chose that as the birthdate—and feast day—of Elizabeth and Zacharias’s son, John the Baptist. When Gabriel later visited Mary to let her know that she’d bear a son, too, he mentioned that Elizabeth was in her sixth month of pregnancy. That means Jesus would’ve been conceived in late March, and born in late December—the night of December 24, to be exact, or the early hours of December 25.

Another theory suggests that Christians arrived at December 25 based on an ancient Jewish idea that prophets die on their birthday. During the 3rd century CE, theologists like Tertullian and Hippolytus dated Jesus’s crucifixion to March 25, since it happened around Passover. But to Sextus Julius Africanus, it was less about when Jesus was born and more about when he first came to Earth; in other words, he believed Jesus’s death and conception coincided on March 25, and thus his birth occurred on December 25 [PDF].

The Early History of Christmas

Even if Zacharias was in the temple on September 24, Gabriel did visit Mary exactly six months later, and Jesus was born right on his due date, it’s still possible that we celebrate Christmas on December 25 for a different reason altogether.

While 3rd-century Christians were busy worshiping the Son of God, some of their pagan counterparts were busy worshiping the Sun God. In the 270s, Roman emperor Aurelian popularized the cult of Sol Invictus, or “The Unconquered Sun,” whose feast day was celebrated on December 25. According to John Carroll University history professor Joseph F. Kelly, other Romans revered a Persian god, Mithra, whose feast day also may have fallen on December 25. There was also Saturnalia, an annual Roman festival that ran from December 17 to December 23. In short, many ancient Romans were well-accustomed to celebrating something in late December by the time Christianity entered the mainstream.

A painting of Saturnalia festivities by Antoine Callet, 1783.Themadchopper, Wikimedia Commons // Public Domain

That happened during Constantine’s rule over Rome in the early 4th century. In 313, Constantine and his fellow ruler Licinius issued the Edict of Milan, which basically legalized Christianity and condemned the ongoing persecution of anyone who practiced it. Constantine was a devout Christian himself, and he spent the rest of his reign spreading the religion throughout the empire. The first known record of December 25 as Jesus’s official birthday is from 336, the year before Constantine died. Because it’s mentioned in a volume containing other important religious dates, some have assumed that a celebration probably occurred on that day, and 336 is often cited as the first known “Christmas.”

Whether Christians celebrated Christmas on December 25 before 336 may forever be unknown, but we do know that the custom quickly caught on (spending the holiday watching A Christmas Story marathon wouldn't come until much later). By the end of the 4th century, Christian bishops were holding Christmas Mass all over Rome, and pagan festivals soon fell out of fashion. The fact that Christmas essentially replaced those earlier December traditions could be a coincidence, but some believe it was by design: Since Romans were already primed for parties on December 25, the Church could’ve been trying to co-opt a built-in subscriber base.

In summary, the origins of Christmas are just as subject to interpretation as Jesus’s actual birthdate—so feel free to play Christmas music whenever you want.

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