On July 8, 2011, the Space Shuttle Atlantis launched on the final mission of the Space Shuttle (STS) program. The mission was designated STS-135.
That final mission carried the smallest shuttle crew since STS-6 in 1983—just four astronauts. They were Chris Ferguson, Doug Hurley, Sandra Magnus, and Rex Walheim.
They were sent up to deliver over 11,600 pounds of equipment and supplies to the International Space Station (ISS). This trip was vital to the ISS, because the end of the Shuttle program meant the end of NASA's ability to deliver heavy payloads to orbit. After the Shuttle, NASA had to rely on commercial launches (not yet in full swing in 2011) and international partners. (Shown at the top of this post is Mission Specialist in the "cupola" of the ISS, observing Earth, while Atlantis was docked with the space station.)
STS-135 was a minor media sensation, with the Obama family visiting Kennedy Space Center prior to the launch, President Obama meeting the crew at the White House, and the crew appearing on The Colbert Report. The Empire State Building was lit in red, white, and blue on July 20 in tribute to the Shuttle program.
In line with NASA tradition, STS-135 received some notable wakeup calls during the mission. Some of the biggies included messages recorded by Beyoncé, Paul McCartney, Michael Stipe, and Elton John, preceding their songs (including a brief a capella version of REM's "Man On the Moon" by Stipe). On the Shuttle's last wakeup call, CAPCOM played "God Bless America" as performed by Kate Smith. It was introduced by astronaut Shannon Lucid. It really was the end of an era.
STS-135 ended when Atlantis landed at Kennedy Space Center in Florida on July 21, 2011. Today, Atlantis remains on display at Kennedy. Of the original five Space Shuttles, it is one of three that remain intact. Discovery is on display in Virginia, and Endeavour is in Los Angeles.