‘Good’ Cholesterol May Not Be So Great After All

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Bad news for good cholesterol: A Danish study published in European Heart Journal finds that people with extremely high high-density lipoprotein (HDL, often called “good” cholesterol) levels face a higher, not lower, risk of death.

Cholesterol as a substance is neither good nor bad, but an important part of our body chemistry. Like most things, in moderation, it's fine; the health risks set in once our levels get out of whack. Scientists and doctors have long understood cholesterol as a sort of angel-on-one-shoulder, devil-on-the-other situation, in which low-density lipoprotein (LDL) is harmful and HDL is helpful. HDL mediates LDL's negative effects, which means that having more HDL is good.

Or at least that's what we thought.

Researchers pulled health information on 116,000 people from the Copenhagen City Heart Study and the Copenhagen General Population Study, then cross-checked it against death reports from the Danish Civil Registration System. They followed study subjects for six years, during which more than 10,500 people died. 

What they found surprised them. Extremely high levels of HDL were associated with significantly greater risks of death than normal levels—68 percent higher for women and a staggering 106 percent for men. Men with very high HDL (one step down from "extremely high") were 36 percent more likely to die.

"These results radically change the way we understand 'good' cholesterol. Doctors like myself have been used to congratulating patients who had a very high level of HDL in their blood. But we should no longer do so, as this study shows a dramatically higher mortality rate," co-author Børge Nordestgaard of the University of Copenhagen said in a statement.

Before we get too worried, it's worth noting that these extremely high HDL levels were incredibly rare, affecting only 0.4 percent of male participants and 0.3 percent of women. The researchers say these people were also more likely to share unusual genetic variants. It's possible that these genes and not the cholesterol are responsible for their higher mortality rates.

Some elements of our ideas about cholesterol still held true. People with extremely low HDL levels also faced an increased mortality risk.

The safest levels seemed to be right in the middle, at 1.9 mmol/L for men and 2.4 mmol/L for women. 

More research is needed, as this study focused exclusively on white Danish people and only looked at correlation, not causation. 

Still, Nordestgaard said, "It appears that we need to remove the focus from HDL as an important health indicator in research, at hospitals and at the general practitioner. These are the smallest lipoproteins in the blood, and perhaps we ought to examine some of the larger ones instead."

A Custom Wheelchair Allowed This Brain-Injured Baby Raccoon to Walk Again

фотограф/iStock via Getty Images
фотограф/iStock via Getty Images

Animal prosthetics and wheelchairs allow dogs, cats, and even zoo animals with limited mobility to walk again, but wild animals with disabilities aren't usually as lucky. Vittles, a baby raccoon rescued in Arkansas, is the rare example of an animal that was severely injured in its natural habitat getting a second shot at life.

As Tribune Media Wire reports, Vittles came to wildlife rehab specialist Susan Curtis, who works closely with raccoons for the state of Arkansas, with a traumatic brain injury at just 8 weeks old. The cause of the trauma wasn't clear, but it was obvious that the raccoon wouldn't be able to survive on her own if returned to the wild.

Curtis partnered with the pet mobility gear company Walkin' Pets to get Vittles back on her feet. They built her a tiny custom wheelchair to give her balance and support as she learned to get around on her own. The video below shows Vittles using her legs and navigating spaces with help from the chair and guidance from her caretaker.

Vittles will likely never recover fully, but now that she's able to exercise her leg muscles, her chance at one day moving around independently is greater than it would have been otherwise. She now lives with her caretaker Susan and a 10-year old raccoon with cerebral palsy named Beetlejuice. After she's rehabilitated, the plan is to one day make her part of Arkansas's educational wildlife program.

[h/t Tribune Media Wire]

Why You Should Never Shower With Your Contact Lenses In

belchonock/iStock via Getty Images
belchonock/iStock via Getty Images

Contact lenses offer a level of convenience for those with less-than-perfect vision that glasses can hardly compete with, but that doesn’t mean the daily struggle of taking them in and out of your eyes doesn’t wear on you. If you get a little lazy and decide it’s fine to leave them in your eyes during showers or pool parties, think again.

According to Popular Science, a 41-year-old woman in the UK lost sight in her left eye as a result of frequently showering and swimming without removing her contacts. The culprit was Acanthamoeba polyphaga, a protozoa that crawled into her eye and caused a cornea infection called Acanthamoeba keratitis. After two months of pain, blurry vision, and light sensitivity, the woman sought medical attention at the Manchester Royal Eye Hospital, where doctors discovered a ring shape in her left eye and a hazy layer covering her cornea. Upon testing her vision, they found that her left eye was now 20/200, which counts as legally blind in the United States.

Leela Raju, an ophthalmologist and cornea specialist at New York University, told Popular Science that the single-celled organisms “can be anywhere,” including pools, hot tubs, showers, dirty saline solution containers, and even tap water. Lens-wearers make up around 85 percent of those who get infected, and experts think it may be because the amoeba can latch onto a contact lens more easily than a bare eye.

Though Popular Science reports that Acanthamoeba keratitis only affects one or two people out of every million contact wearers each year, that’s no reason not to be careful. If you do catch it, you’ll likely need a cornea transplant, and even that won’t necessarily restore your eyesight to its previous state—after her transplant, the UK woman’s left eye now has 20/80 vision.

“It’s just a long road, for something that’s totally preventable,” Raju says. In addition to removing your contacts before swimming, showering, or sleeping, you should also refrain from reusing saline solution, make sure your contact case is completely clean and dry before filling it with more solution, and check out these other tips.

[h/t Popular Science]

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