4 Diseases Caused by a Lack of Essential Vitamins and Minerals

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Companies pushing products with added vitamins and minerals can fool people into thinking that they’re eating a “healthy” food when they’re not—but it’s not like those vitamins and minerals are there for no reason. For much of human history, diseases of nutrient deficiency were the norm, and in some parts of the world, they still persist. Even into the 20th century, conditions caused by a lack of certain vitamins or minerals were endemic to North America and Europe. Artificially added nutrients may not make a food “healthy,” but they do stave off several debilitating, and sometimes fatal, diseases of malnutrition. Here are a few of those maladies.

1. Scurvy

The disease of pirates: the grey-death. Scurvy is caused by a lack of vitamin C, whose chemical name, ascorbic acid, is derived from the Latin term for scurvy, scorbutus. Even though the disease was known since ancient times (described by Hippocrates around 400 BCE), it was not a scourge to those who were largely land-bound. Even though its causes were unknown, many cultures realized that eating certain herbs could reverse the symptoms, and as long as there was access to fresh food, it was generally kept under control.

Scurvy didn’t become a significant problem until the Age of Discovery (beginning in the 15th century), when people at sea were not able to access that much-needed fresh food for months at a time. Preserved meats and carbohydrates contained no vitamin C, and unlike most animals, the human body is not able to create vitamin C on its own.

The early symptoms of scurvy include spongy gums, pain in the joints, and blood spots appearing under the skin. As the disease progressed, the teeth would become loose, extreme halitosis (bad breath) would develop, the afflicted would become too weak to walk or work, be in too much pain to eat, and would die “mid-sentence,” often from a burst blood vessel. Many of the early explorers lost great numbers of men to scurvy: Vasco de Gama lost 116 out of 170 men in 1499, and in 1520, Magellan lost 208 out of 230. A few deaths were attributable to other causes, but the vast majority were due to scurvy.

Despite not being able to pinpoint the exact cause of scurvy, in the 18th century, naval physician James Lind was able to prove, in what’s considered to be the first controlled scientific experiment, that scurvy could be prevented (and cured) by incorporating citrus fruits such as limes and oranges into the diet of sailors. Although his findings weren’t widely accepted at first, the British Navy eventually began issuing standard rations of lemon juice, and later, limes, to their sailors—which gave rise to the term “limey” in reference to the British.

These days, scurvy is an extremely rare condition, almost exclusively caused by someone eating a completely unvaried diet. In most cases, high levels of oral supplementation of vitamin C are enough to reverse the condition in a matter of weeks, and death by scurvy is almost unheard of.

2. Rickets

This condition is brought on by a lack of vitamin D, which causes the body to be unable to absorb or deposit calcium. Less commonly, it can also be caused by a lack of calcium or phosphorus, but vitamin D deficiency is by far the most common cause. Unlike vitamin C, the human body is able to produce vitamin D, but only if it has the metabolic precursors available to it.

When the skin is exposed to ultraviolet light (such as from the sun), cholesterol in the skin reacts and forms cholecalciferol, which is then processed in the liver and kidneys to create the active form of vitamin D. Even with a nominally healthy diet, without enough sun exposure, the body can’t produce the vitamin D precursors on its own. This is actually re-emerging as a health concern among some increasingly-indoor groups of people, and is one of the few hypovitaminosis (lack of vitamin) conditions not considered to be a “disease of the past.” Luckily, when the deficiency is recognized, cholecalciferol can be directly taken as a vitamin supplement or acquired from eating organ meats and oils, such as cod liver oil, allowing the body to resume producing vitamin D.

Rickets is a condition of children, as the deficiency’s most severe effects are on developing bones; in adults, “bone-softening,” or osteomalacia, can be caused by the same vitamin deficiency. But in adults, it both takes significantly longer to develop and tends to cause tip-off signs that something is wrong before bone warping sets in, such as extreme pain in the bones, and unexplained muscle weakness. In children, especially those that don’t or can’t receive regular check-ups, deformity and debilitation by the deficiency is often only noticed after significant damage has been done to their developing skeletons.

The most telling symptoms of rickets are at the epiphyses (growth plates) of bones: The body is unable to lengthen bones by depositing calcium, and ends up with bones that flare outward in a “cupping” appearance. This leads to costochondral swelling, or what’s known as the “rachitic rosary” along the ribcage of the child, as well as widened wrists and “thick” joints. Before widened wrists or rachitic rosary appears, the softening of the skull bones can lead to “Caput Quadratum”—a square-headed appearance, and often the first sign of skeletal growth problems. If left untreated, rickets also can cause an extremely curved back, stunted growth, and frequent fractures—all of which can lead to permanent and debilitating deformity.

3. Beriberi

This condition is largely confined to Asia, especially in countries where boiled rice is a staple. The Sinhalese term “beri-beri” means, “I cannot, I cannot,” and derives from the inability to perform even the simplest of tasks once the polyneuritis (nerve inflammation) caused by the deficiency of vitamin B1 (thiamine) has permanently damaged the neurons, when the condition has progressed to the end-stage.

Although beriberi was known to exist in rice-eating countries several centuries back, its prevalence boomed with the introduction of steam-driven rice-polishing mills from Europe. The superior taste of the milled white rice led many locals to abandon the local (unpolished) brown rice, and in doing so, abandon their primary source of thiamine. From the 1860s to the turn of the 20th century, people whose plant consumption was limited to the polished white rice would often come down with weakness, pain, weight loss, difficulty walking, and emotional disturbances. Beriberi became one of the leading causes of mortality in the region.

In the 1880s, a doctor named Christiaan Eijkman began researching the causes of this epidemic at a laboratory in the Dutch East Indies (now Jakarta, Indonesia), and initially believed that the condition was caused by a bacterial infection. However, after years of study, he came to the conclusion that “white rice is poisonous.” He discovered this by feeding a group of chickens solely white rice, and another group unpolished brown rice. The chickens that ate the white rice came down with beriberi-like symptoms, while the others stayed healthy. Eijkman also discovered that when the chickens fed white rice were subsequently fed brown rice, they recovered from their illness! Later dietary testing on prisoners confirmed his results. Even though he didn’t know the cause of the condition, Eijkman proved that white rice was the culprit, and shared the 1929 Nobel Prize in Medicine for his discovery.

Beriberi is occasionally seen in the modern world, but its primary cause is chronic alcoholism—the poor diets of some chronic alcoholics, combined with the decreased absorption of what thiamine is consumed, leads to symptoms that unfortunately are sometimes left undiagnosed until it’s too late. Recently, beriberi was also seen in Haitian prisons when the prison system began buying imported polished rice from the United States, and stopped feeding their inmates the local brown rice.

4. Pellagra

What causes blistering of the skin in the sun, pale skin, a craving for raw meat, blood dripping from the mouth, aggression, and insanity? If you answered “vampirism,” you’re close—the myth of the vampire may have its roots in the condition known as “pellagra.”

Pellagra is caused by a lack of vitamin B3 (niacin). First identified and commonly diagnosed in the Asturian Empire (now Northern Spain), it was originally called “Asturian leprosy.” However, the condition was seen throughout Europe, the Middle East, and North Africa, wherever a large percentage of food energy was derived from corn, and fresh meat was not available. The area of highest prevalence was Northern Italy, where Francesco Frapoli of Milan called it “pelle agra,” meaning “sour skin.”

It was initially believed that either the corn itself, or some insect associated with corn, was causing pellagra. This belief was reinforced when much of France eliminated corn as a food staple and virtually eradicated the condition. Between the era that corn was introduced to Europe (the early 16th century) and the late 19th century, pellagra was found almost everywhere that poor people subsisted on cornmeal and little else.

Around the turn of the 20th century, people began to notice that despite subsisting on just as much corn as poor Europeans, poor Mesoamerican natives didn’t come down with the condition. It was eventually discovered that this was because the traditional processing of corn in the Americas involved “nixtamalization,” in which the kernels were soaked in limewater before hulling them. The alkali solution freed up the niacin that was present in the grain, but previously inaccessible.

Despite the extensive work of Dr. Joseph Goldberger in the 1910s and 1920s, which proved that pellagra wasn’t caused by a germ but by a dietary deficiency, the condition was occurring in epidemic proportions in the rural Southern US until the 1940s.

Today, pellagra is most common in the poorest regions of the world, especially places that rely upon food aid programs. Some countries still ship unfortified cornmeal rather than corn masa (nixtamalized corn) or fortified cornmeal to developing countries or to their own impoverished populations. China, parts of Africa, Indonesia, and North Korea all have endemic pellagra among their lowest classes.

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The discovery of important vitamins and how to produce them has been so significant to human health that many of those who were integral to the discoveries have been awarded the Nobel Prize in Medicine; more than 10 Nobel Prizes have been divided among almost 20 eminent scientists for the discovery or isolation of vitamins A, B1, B12, C, D, E, and K. Over the second half of the 20th century, after the beginning of widespread supplementation to everyday food items, the incidences of the conditions covered here went down dramatically across much of the world.

Of course, the minerals essential to the human body play similarly important roles in maintaining health. However, humans have not historically had a widespread significant problem acquiring these nutrients, as most plants absorb many minerals from the soil. With the increased processing of our food throughout the 20th century, however, some of these minerals have been lost, and have had to be re-added to the average Western diet through supplementation. In the rest of the world, displacement due to war, and unfortified food from aid programs, has left survivors with enough calories, but not enough nutrients. Supplementation of assistance food and local fortification of salt and flour is beginning to help give displaced people (especially displaced children) a new chance at life without these and other nutritional diseases.

In the developed world, you won’t be the healthiest bloke on the block if you eat nothing but breakfast cereal and cartons of juice—but the food industry has ensured that you at least won’t die of malnutrition. Even people with healthy diets benefit from the supplementation of vitamins and minerals in common foodstuffs, and adding the nutrients costs next to nothing. Doctors and nutritionists still agree that the healthiest way to acquire your necessary vitamins and minerals is by eating a balanced diet and spending time outdoors each day, but in the course of modern life, that’s not always possible, and if people are going to eat poorly either way, we may as well keep them from dropping dead of scurvy!

7 Quick Tips for Disinfecting Your Home the Smart Way

Frequent cleaning of high-traffic areas can reduce the spread of illness in your home.
Frequent cleaning of high-traffic areas can reduce the spread of illness in your home.
BrianAJackson/iStock via Getty Images

With many people spending more time—or virtually all of their time—indoors, it’s natural for thoughts to turn to how to best clean surfaces that might help minimize the risk of spreading illness. Although researchers believe respiratory droplets are the primary way coronavirus is transmitted, preliminary data, which is not yet peer-reviewed, suggests the virus may remain on some surfaces for hours or days.

While scrubbing isn't a complex process, there are nonetheless some areas of your home you might be neglecting. Here’s how to best approach a household scrub, as well as identify and disinfect some common germ hot spots.

1. Pay attention to high-touch surfaces and clean them frequently.

High-touch surfaces are exactly what they sound like: Areas in the home that get handled and touched regularly. Think doorknobs, light switches, appliance handles, toilet handles, faucets, and remotes. And don’t forget laptops, keyboards, desks, and phones.

2. Don't just do a quick wipe down. Get the entire surface.

Taking a disinfecting wipe to the keyhole of a doorknob isn’t going to do you much good—it's important to really scrub all high-touch surfaces. Make sure you get every available surface area, including the plate behind the knob where fingers and hands often brush against it. When cleaning remotes, make sure you don't just scrub the buttons, but the space between them as well.

3. You can use soap and water.

While products claiming to kill 99.9 percent of germs are best in this scenario, there's another option if you're having a hard time tracking down those supplies—simply mix some dish soap in water. It won’t kill organisms, but it can remove them from the surface. (And while soap and water can work for high-touch surfaces throughout the home, you shouldn't use the solution on electronics like your remote or keyboard.)

If you’re looking to kill germs, diluted bleach (four teaspoons to one quart of water) and 70 percent alcohol solutions work well. But it's important to note that bleach and other cleaners can harm certain surfaces. So be sure to do your research and make sure the product you're using won't cause any damage before you start scrubbing.

4. Take laundry precautions.

If you’re trying to be extra-vigilant about the spread of germs in the house, you should consider washing clothes at the highest possible temperature and disinfecting laundry bins. It’s also advisable to use disposable laundry bags.

5. Remove your shoes before entering the house.

This step is more preventative, but it’s a simple way to keep from tracking in contaminants. Remove your shoes before going inside and leave them near the door. It's also a good idea to clean floor surfaces with disinfecting mop cloths, but be sure anything you use is safe for the finished surface. Cleaners like bleach can discolor certain materials.

6. Don't forget to clean your car.

Even people vigilant about cleaning their home can neglect their car interior. Since you’re constantly touching virtually every surface, be sure to wipe everything down regularly, including the steering wheel and door handles. If you have a leather interior, there are auto wipes available for those surfaces. And before you go wipe down any touchscreens, be sure to check your owner’s manual to see if they require any special microfiber cloth.

7. Give your debit cards a wipe.

It’s a good idea to disinfect credit or debit cards that follow you around on shopping excursions. As with all high-touch objects, be sure to wipe them down every day.

[h/t New York Times]

15 Facts About John Brown, the Real-Life Abolitionist at the Center of The Good Lord Bird

John Brown, circa 1846.
John Brown, circa 1846.
Augustus Washington/Public Domain via Wikimedia Commons

Abolitionist John Brown's raid on Harpers Ferry on October 16, 1859, was meant to start an armed slave revolt, and ultimately end slavery. Though Brown succeeded in taking over the federal armory, the revolt never came to pass—and Brown paid for the escapade with his life.

In the more than 160 years since that raid, John Brown has been called a hero, a madman, a martyr, and a terrorist. Now Showtime is exploring his legacy with an adaption of James McBride’s The Good Lord Bird. Like the novel it’s based on, the miniseries—which stars Ethan Hawke—will cover the exploits of Brown and his allies. Here's what you should know about John Brown before you watch.

1. John Brown was born into an abolitionist family on May 9, 1800.

John Brown was born to Owen and Ruth Mills Brown in Torrington, Connecticut, on May 9, 1800. After his family relocated to Hudson, Ohio (where John was raised), their new home would become an Underground Railroad station. Owen would go on to co-found the Western Reserve Anti-Slavery Society and was a trustee at the Oberlin Collegiate Institute, one of the first American colleges to admit black (and female) students.

2. John Brown declared bankruptcy at age 42.

At 16, Brown went to school with the hope of becoming a minister, but eventually left the school and, like his father, became a tanner. He also dabbled in surveying, canal-building, and the wool trade. In 1835, he bought land in northeastern Ohio. Thanks partly the financial panic of 1837, Brown couldn’t satisfy his creditors and had to declare bankruptcy in 1842. He later tried peddling American wool abroad in Europe, where he was forced to sell it at severely reduced prices. This opened the door for multiple lawsuits when Brown returned to America.

3. John Brown's Pennsylvania home was a stop on the Underground Railroad.

The John Brown Tannery Site in Pennsylvania
The John Brown Tannery Site in Pennsylvania.
Public Domain, Wikimedia Commons

Sometime around 1825, Brown moved himself and his family to Guys Mills, Pennsylvania, where he set up a tannery and built a house and a barn with a hidden room that was used by slaves on the run. Brown reportedly helped 2500 slaves during his time in Pennsylvania; the building was destroyed in 1907 [PDF], but the site, which is now a museum that is open to the public, is on the National Register of Historic Places. Brown moved his family back to Ohio in 1836.

4. After Elijah Lovejoy's murder, John Brown pledged to end slavery.

Elijah Lovejoy was a journalist and the editor of the St. Louis/Alton Observer, a staunchly anti-slavery newspaper. His editorials enraged those who defended slavery, and in 1837, Lovejoy was killed when a mob attacked the newspaper’s headquarters.

The incident lit a fire under Brown. When he was told about Lovejoy’s murder at an abolitionist prayer meeting in Hudson, Brown—a deeply religious man—stood up and raised his right hand, saying “Here, before God, in the presence of these witnesses, from this time, I consecrate my life to the destruction of slavery."

5. John Brown moved to the Kansas Territory after the passage of the Kansas-Nebraska Act.

In 1854, Congress passed the Kansas-Nebraska Act, which decreed that it would be the people of Kansas and Nebraska who would decide if their territories would be free states or slave states. New England abolitionists hoping to convert the Kansas Territory into a Free State moved there in droves and founded the city of Lawrence. By the end of 1855, John Brown had also relocated to Kansas, along with six of his sons and his son-in-law. Opposing the newcomers were slavery supporters who had also arrived in large numbers.

6. John Brown’s supporters killed five pro-slavery men at the 1856 Pottawatomie Massacre.

A John Brown mural by John Steuart Curry
A John Brown mural by John Steuart Curry.
Public Domain, Wikimedia Commons

On May 21, 1856, Lawrence was sacked by pro-slavery forces. The next day, Charles Sumner, an anti-slavery Senator from Massachusetts, was beaten with a cane by Representative Preston Brooks on the Senate floor until he lost consciousness. (A few days earlier, Sumner had insulted Democratic senators Stephen Douglas and Andrew Butler in his "Crime Against Kansas" speech; Brooks was a representative from Butler’s state of South Carolina.)

In response to those events, Brown led a group of abolitionists into a pro-slavery settlement by the Pottawatomie Creek on the night of May 24. On Brown’s orders, five slavery sympathizers were forced out of their houses and killed with broadswords.

Newspapers across the country denounced the attack—and John Brown in particular. But that didn't dissuade him: Before his final departure from Kansas in 1859, Brown participated in many other battles across the region. He lost a son, Frederick Brown, in the fighting.

7. John Brown led a party of liberated slaves all the way from Missouri to Michigan.

In December 1858, John Brown crossed the Kansas border and entered the slave state of Missouri. Once there, he and his allies freed 11 slaves and led them all the way to Detroit, Michigan, covering a distance of more than 1000 miles. (One of the liberated women gave birth en route.) Brown’s men had killed a slaveholder during their Missouri raid, so President James Buchanan put a $250 bounty on the famed abolitionist. That didn’t stop Brown, who got to watch the people he’d helped free board a ferry and slip away into Canada.

8. John Brown’s raid on Harpers Ferry was meant to instigate a nationwide slave uprising.

On October 16, 1859, Brown and 18 men—including five African Americans—seized control of a U.S. armory in the Jefferson County, Virginia (today part of West Virginia) town of Harpers Ferry. The facility had around 100,000 weapons stockpiled there by the late 1850s. Brown hoped his actions would inspire a large-scale slave rebellion, with enslaved peoples rushing to collect free guns, but the insurrection never came.

9. Robert E. Lee played a part in John Brown’s arrest.

Artist Thomas Hovenden depicts John Brown after his capture.
Artist Thomas Hovenden depicts John Brown after his capture.
The Print Collector/Print Collector/Getty Images

Shortly after Brown took Harpers Ferry, the area was surrounded by local militias. On the orders of President Buchanan, Brevet Colonel Robert E. Lee entered the fray with a detachment of U.S. Marines. The combined might of regional and federal forces proved too much for Brown, who was captured in the Harpers Ferry engine house on October 18, 1859. Ten of Brown's men died, including two more of his sons.

10. John Brown was put on trial a week after his capture.

After his capture, Brown—along with Aaron Stevens, Edwin Coppoc, Shields Green, and John Copeland—was put on trial. When asked if the defendants had counsel, Brown responded:

"Virginians, I did not ask for any quarter at the time I was taken. I did not ask to have my life spared. The Governor of the State of Virginia tendered me his assurance that I should have a fair trial: but, under no circumstances whatever will I be able to have a fair trial. If you seek my blood, you can have it at any moment, without this mockery of a trial. I have had no counsel: I have not been able to advise with anyone ... I am ready for my fate. I do not ask a trial. I beg for no mockery of a trial—no insult—nothing but that which conscience gives, or cowardice would drive you to practice. I ask again to be excused from the mockery of a trial."

Brown would go on to plead not guilty. Just days later, he was found “guilty of treason, and conspiring and advising with slaves and others to rebel, and murder in the first degree” and was sentenced to hang.

11. John Brown made a grim prophecy on the morning of his death.

On the morning of December 2, 1859, Brown passed his jailor a note that read, “I … am now quite certain that the crimes of this guilty land will never be purged away, but with blood.” He was hanged later that day.

12. Victor Hugo defended John Brown.

Victor Hugo—the author of Les Misérables and The Hunchback of Notre Dame, who was also an abolitionist—penned an open letter on John Brown’s behalf in 1859. Desperate to see him pardoned, Hugo wrote, “I fall on my knees, weeping before the great starry banner of the New World … I implore the illustrious American Republic, sister of the French Republic, to see to the safety of the universal moral law, to save John Brown.” Hugo’s appeals were of no use. The letter was dated December 2—the day Brown was hanged.

13. Abraham Lincoln commented on John Brown's death.

Abraham Lincoln, who was then in Kansas, said, “Old John Brown has been executed for treason against a State. We cannot object, even though he agreed with us in thinking slavery wrong. That cannot excuse violence, bloodshed and treason. It could avail him nothing that he might think himself right.”

14. John Brown was buried in North Elba, New York.

John Brown's gravesite in New York
John Brown's gravesite in New York.
Public Domain, Wikimedia Commons

In 1849, Brown had purchased 244 acres of property from Gerrit Smith, a wealthy abolitionist, in North Elba, New York. The property was near Timbuctoo, a 120,000-acre settlement that Smith had started in 1846 to give African American families the property they needed in order to vote (at that time, state law required black residents to own $250 worth of property to cast a vote). Brown had promised Smith that he would assist his new neighbors in cultivating the mountainous terrain.

When Brown was executed, his family interred the body at their North Elba farm—which is now a New York State Historic Site.

15. The tribute song "John Brown's Body" shares its melody with “The Battle Hymn of the Republic.”

It didn’t take long for Brown to become a martyr. Early in the 1860s, the basic melody of “Say Brothers Will You Meet Us,” a popular camp hymn, was fitted with new lyrics about the slain abolitionist. Titled “John Brown’s Body,” the song spread like wildfire in the north—despite having some lines that were deemed unsavory. Julia Ward Howe took the melody and gave it yet another set of lyrics. Thus was born “The Battle Hymn of the Republic,” a Union marching anthem that's still widely known today.

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