Scientists Create Three Puppy Clones of 'Snuppy,' the World's First Cloned Dog

Courtesy of Nature
Courtesy of Nature

Snuppy, the world's first cloned dog, died in 2015, but his genetic legacy lives on. As the National Post reports, South Korean scientists recently described in the journal Scientific Reports the birth of three clone puppies, all of which are identical replicas of the famous Afghan hound.

Those who lived through the 1990s might remember Dolly, the Scottish sheep that gained fame for being the very first mammal to be cloned from an adult cell. Following Dolly's 1996 cloning, scientists managed to replicate other animals, including cats, mice, cows, and horses. But dog cloning initially stymied scientists, Time reports, as their breeding period is limited and their eggs are also hard to extract.

Ultimately, researchers ended up using somatic cell nuclear transfer (SCNT) to clone a dog, the same method that was used to make Dolly. In the early 2000s, a team of South Korean scientists inserted DNA harvested from an Afghan hound's skin cells into a dog egg from which the DNA had been removed. The egg divided, which produced multiple cloned embryos.

The scientists implanted 1095 of these embryos in 123 dogs, an exhaustive initiative that yielded just three pregnancies, according to NPR. Of these, Snuppy—whose name is a combination of "puppy" and Seoul National University's initials—was the only survivor.

Snuppy died from cancer in April 2015, just shortly after his 10th birthday. To celebrate his successful life, the same South Korean researchers decided to re-clone him using mesenchymal stem cells from the dog's belly fat, which were taken when he was five. This time around, they transferred 94 reconstructed embryos to seven dogs. Four clones were later born, although one ended up dying shortly after birth.

The tiny Snuppy clones are now more than a year old, and researchers say that they don't think that the pups face the risk of accelerated aging, nor are they more disease-prone than other dogs. (Dolly died when she was just six years old, while cloned mice have also experienced shorter lifespans.) Snuppy's somatic cell donor, Tai, lived just two years longer than Snuppy, dying at age 12, the average lifespan of an Afghan hound.

Researchers say that this new generation of Snuppys will yield new insights into the health and longevity of cloned animals. Meanwhile, in other animal cloning news, a Texas-based company called ViaGen Pets is now offering to clone people's beloved pets, according to CBS Pittsburgh—a service that costs a cool $50,000 for dogs.

[h/t National Post]

Amazon's Best Black Friday Deals: Tech, Video Games, Kitchen Appliances, Clothing, and More

Amazon
Amazon

This article contains affiliate links to products selected by our editors. Mental Floss may receive a commission for purchases made through these links.

Black Friday is finally here, and Amazon is offering great deals on kitchen appliances, tech, video games, and plenty more. We will keep updating this page as sales come in, but for now, here are the best Amazon Black Friday sales to check out.

Kitchen

Instant Pot/Amazon

- Instant Pot Duo Plus 9-in-115 Quart Electric Pressure Cooker; $90 (save $40)

- Keurig K-Cafe Special Edition; $190 (save $30)

- Ninja OS301 Foodi 10-in-1 Pressure Cooker and Air Fryer; $125 (save $75)

- Nespresso Vertuo Next Coffee and Espresso Machine by Breville; $120 (save $60)

- KitchenAid KSMSFTA Sifter with Scale Attachment; $95 (save $75)

- Keurig K-Mini Coffee Maker; $60 (save $20)

- Cuisinart Bread Maker; $80 (save $97)

- Anova Culinary Sous Vide Precision Cooker; $139 (save $60)

- Aicook Juicer Machine; $35 (save $15)

- JoyJolt Double Wall Insulated Espresso Mugs - Set of Two; $14 (save $10)

- Longzon Silicone Stretch Lids - Set of 14; $16 (save $11)

- HadinEEon Milk Frother; $37 (save $33)

Home Appliances

Roomba/Amazon

- iRobot Roomba 675 Robot Vacuum with Wi-Fi Connectivity; $179 (save $101)

- ASAKUKI 500ml Premium Essential Oil Diffuser; $22 (save $4)

- Facebook Portal Smart Video Calling 10 inch Touch Screen Display with Alexa; $129 (save $50)

- Bissell air320 Smart Air Purifier with HEPA and Carbon Filters; $280 (save $50)

- Oscillating Quiet Cooling Fan Tower; $59 (save $31)

- TaoTronics PTC 1500W Fast Quiet Heating Ceramic Tower; $55 (save $10)

- Vitamix 068051 FoodCycler 2 Liter Capacity; $300 (save $100)

- Ring Video Doorbell; $70 (save $30)

Video games

Sony

- Marvel's Spider-Man: Game of The Year Edition for PlayStation 4; $20 (save $20)

- The Legend of Zelda: Link's Awakening; $40 (save $20)

- Hyrule Warriors: Age of Calamity; $50 (save $10)

- Marvel's Avengers; $25 (save $33)

- The Last of Us Part II for PlayStation 4; $30 (save $30)

- LEGO Harry Potter: Collection; $15 (save $15)

- Ghost of Tsushima; $40 (save $20)

- BioShock: The Collection; $20 (save $30)

- The Sims 4; $24 (save $20)

- God of Warfor PlayStation 4; $10 (save $10)

- Days Gonefor PlayStation 4; $20 (save $6)

- Luigi's Mansion 3 for Nintendo Switch; $40 (save $20)

Computers and tablets

Microsoft/Amazon

- New Apple MacBook Pro 16 inches with 512 GB; $2149 (save $250)

- Microsoft Surface Laptop 3 with 13.5 inch Touch-Screen; $1200 (save $400)

- Lenovo ThinkPad T490 Laptop; $889 (save $111)

- Amazon Fire HD 10 Tablet (64GB); $120 (save $70)

- Amazon Fire HD 10 Kids Edition Tablet (32 GB); $130 (save $70)

- Apple iPad Mini (64 GB); $335 (save $64)

- Vankyo MatrixPad S2 Tablet; $120 (save $10)

Tech, gadgets, and TVs

Apple/Amazon

- Apple Watch Series 3 with GPS; $120 (save $79)

- Seneo Wireless Charger, 3 in 1 Wireless Charging Station; $16 (save $10)

- SAMSUNG 75-inch Class Crystal 4K Smart TV; $998 (save $200)

- Nixplay 2K Smart Digital Picture Frame 9.7 Inch Silver; $238 (save $92)

- All-New Amazon Echo Dot with Clock and Alexa (4th Gen); $39 (save $21)

- MACTREM LED Ring Light 6" with Tripod Stand; $16 (save $3)

- Amazon Fire TV Stick with Alexa Voice Remote; $28 (save $12)

- DR. J Professional HI-04 Mini Projector; $93 (save $37)

Headphones and speakers

Beats/Amazon

- Beats Solo3 Wireless On-Ear Headphones; $120 (Save $80)

- Apple AirPods Pro; $169 (save $50)

- Anker Soundcore Upgraded Bluetooth Speaker; $22 (save $8)

- Powerbeats Pro Wireless Earphones; $175 (save $75)

- JBL Boombox; $280 (save $120)

Movies and TV

HBO/Amazon

- Game of Thrones: The Complete Series; $115 (save $89)

- Jurassic World 5-Movie Set; $23 (save $37)

- Deadwood: The Complete Series; $42 (save $28)

- Back to the Future Trilogy; $15 (save $21)

Toys and Games

Amazon

- Awkward Family Photos Greatest Hits; $15 (save $10)

- Exploding Kittens Card Game; $10 (save $10)

- Cards Against Humanity: Hidden Gems Bundle; $14 (save $5)

- LOL Surprise OMG Remix Pop B.B. Fashion Doll; $29 (save $6)

- LEGO Ideas Ship in a Bottle 92177 Expert Building Kit; $56 (save $14)

Furniture

Casper/Amazon

- Casper Sleep Element Queen Mattress; $476 (save $119)

- ZINUS Alexis Deluxe Wood Platform Bed Frame; $135 (save $24)

- ROMOON Dresser Organizer with 5 Drawers; $59 (save $11) 

- AmazonBasics Room Darkening Blackout Window Curtains; $26 (save $5)

- Writing Desk by Caffoz; $119 (save $21)

- SPACE Seating Office Support Managers Chair; $112 (save $116)

- Rivet Globe Stick Table Lamp; $53 (save $17)

- Christopher Knight Home Merel Mid-Century Modern Club Chair; $188 (save $10)

- Walker Edison Furniture Industrial Rectangular Coffee Table; $121 (save $48)

Beauty

Haus/Amazon

- MySmile Teeth Whitening Kit with LED Light; $21 (save $12) 

- Cliganic USDA Organic Lip Balms Set of Six; $6 (save $4)

- HAUS LABORATORIES By Lady Gaga: LE RIOT LIP GLOSS; $7 (save $11)

- Native Deodorant for Men and Women Set of Three; $25 (save $11) 

- BAIMEI Rose Quartz Jade Roller & Gua Sha; $14 (save $3)

- Honest Beauty Clearing Night Serum with Pure Retinol and Salicylic Acid; $20 (save $8)

- WOW Apple Cider Vinegar Shampoo and Hair Conditioner Set; $30 (save $5) 

- La Roche-Posay Effaclar Purifying Foaming Gel Cleanser; $15 (save $5)

- wet n wild Bretman Rock Shadow Palette; $9 (save $6)

- EltaMD UV Daily Tinted Face Sunscreen Moisturizer with Hyaluronic Acid; $25 (save $6)

Clothes

Ganni/Amazon

- Ganni Women's Crispy Jacquard Dress; $200 (save $86) 

- The Drop Women's Maya Silky Slip Skirt; $36 (save $9)

- Steve Madden Women's Editor Boot; $80 (save $30)

- adidas Women's Roguera Cross Trainer; $40 (save $25)

- Line & Dot Women's Elizabeth Sweater; $74 (save $18)

- Levi's Men's Sherpa Trucker Jacket; $57 (save $41)

- Adidas Men's Essentials 3-Stripes Tapered Training Joggers Sweatpants; $28 (save $12)

- Timex Men's Weekender XL 43mm Watch; $32 (save $20)

- Ray-Ban Unisex-Adult Hexagonal Flat Lenses Sunglasses; $108 (save $46) 

- Reebok Men's Flashfilm Train Cross Trainer; $64 (save $16)

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How Much Is the Earth Worth?

The New York Public Library, Unsplash
The New York Public Library, Unsplash

Our home planet may be the most precious place we know, but it isn't priceless. The Earth's resources and the value it offers to humans add up to some unknown, tangible cost. The species may never have to worry about buying or selling the world, but thinking of it in terms of concrete numbers can help us better understand its value. Now, as Treehugger reports, one scientist has developed a special formula that allows us to do just that.

According to the calculations of Greg Laughlin, an assistant astronomy and astrophysics professor from the University of California, Santa Cruz, the Earth is worth roughly $5 quadrillion (or $5,000,000,000,000,000). He came up with that price after gauging the planet's mass, temperature, age, and other factors that directly correlate to its ability to sustain life.

To emphasize just how valuable the Earth is, Laughlin also estimated the worth of other planets in our solar system. Our nearest neighbor Mars costs about the same as a used car at $16,000. That's a fortune compared to Venus, which he appraised at the meager value of one cent.

Laughlin doesn't expect these numbers to have applications in the real world. Rather, he hopes they will inspire people to better appreciate the only home they know. He's not the first person to put a massive, hypothetical price tag on something just for fun. The cost of the Death Star from Star Wars has been calculated at $852 quadrillion—many times Laughlin's estimate for Earth.

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