New Patient Test Could Suggest Whether Therapy or Meds Will Work Better for Anxiety

iStock
iStock

Like many psychological disorders, there's no one-size-fits-all treatment for patients with anxiety. Some might benefit from taking antidepressants, which boost mood-affecting brain chemicals called neurotransmitters. Others might respond better to therapy, and particularly a form called cognitive behavioral therapy, or CBT.

Figuring out which form of treatment works best often requires months of trial and error. But experts may have developed a quick clinical test to expedite this process, suggests a new study published in the journal Neuropsychopharmacology.

Researchers at the University of Illinois at Chicago have noted that patients with higher levels of anxiety exhibit more electrical activity in their brains when they make a mistake. They call this phenomenon error-related negativity, or ERN, and measure it using electroencephalography (EEG), a test that records the brain's electric signals.

“People with anxiety disorders tend to show an exaggerated neural response to their own mistakes,” the paper’s lead author, UIC psychiatrist Stephanie Gorka, said in a news release. “This is a biological internal alarm that tells you that you've made a mistake and that you should modify your behavior to prevent making the same mistake again. It is useful in helping people adapt, but for those with anxiety, this alarm is much, much louder.”

Gorka and her colleagues wanted to know whether individual differences in ERN could predict treatment outcomes, so they recruited 60 adult volunteers with various types of anxiety disorders. Also involved was a control group of 26 participants with no history of psychological disorders.

Psychiatrists gauged subjects’ baseline ERN levels by having them wear an EEG cap while performing tricky computer tasks. Ultimately, they all made mistakes thanks to the game's challenging nature. Then, randomized subjects with anxiety disorders were instructed to take an SSRI antidepressant every day for three months, or receive weekly cognitive behavioral therapy for the same duration. (Cognitive behavioral therapy is a type of evidence-based talk therapy that forces patients to challenge maladaptive thoughts and develop coping mechanisms to modify their emotions and behavior.)

After three months, the study's patients took the same computer test while wearing EEG caps. Researchers found that those who'd exhibited higher ERN levels at the study's beginning had reduced anxiety levels if they'd been treated with CBT compared to those treated with medication. This might be because the structured form of therapy is all about changing behavior: Those with enhanced ERN might be more receptive to CBT than other patients, as they're already preoccupied with the way they act.

EEG equipment sounds high-tech, but it's relatively cheap and easy to access. Thanks to its availability, UIC psychiatrists think their anxiety test could easily be used in doctors’ offices to measure ERN before determining a course of treatment.

Looking to Downsize? You Can Buy a 5-Room DIY Cabin on Amazon for Less Than $33,000

Five rooms of one's own.
Five rooms of one's own.
Allwood/Amazon

If you’ve already mastered DIY houses for birds and dogs, maybe it’s time you built one for yourself.

As Simplemost reports, there are a number of house kits that you can order on Amazon, and the Allwood Avalon Cabin Kit is one of the quaintest—and, at $32,990, most affordable—options. The 540-square-foot structure has enough space for a kitchen, a bathroom, a bedroom, and a sitting room—and there’s an additional 218-square-foot loft with the potential to be the coziest reading nook of all time.

You can opt for three larger rooms if you're willing to skip the kitchen and bathroom.Allwood/Amazon

The construction process might not be a great idea for someone who’s never picked up a hammer, but you don’t need an architectural degree to tackle it. Step-by-step instructions and all materials are included, so it’s a little like a high-level IKEA project. According to the Amazon listing, it takes two adults about a week to complete. Since the Nordic wood walls are reinforced with steel rods, the house can withstand winds up to 120 mph, and you can pay an extra $1000 to upgrade from double-glass windows and doors to triple-glass for added fortification.

Sadly, the cool ceiling lamp is not included.Allwood/Amazon

Though everything you need for the shell of the house comes in the kit, you will need to purchase whatever goes inside it: toilet, shower, sink, stove, insulation, and all other furnishings. You can also customize the blueprint to fit your own plans for the space; maybe, for example, you’re going to use the house as a small event venue, and you’d rather have two or three large, airy rooms and no kitchen or bedroom.

Intrigued? Find out more here.

[h/t Simplemost]

This article contains affiliate links to products selected by our editors. Mental Floss may receive a commission for purchases made through these links.

The Psychological Tricks Disney Parks Use to Make Long Wait Times More Bearable

© Jorge Royan, Wikimedia Commons // CC BY-SA 3.0
© Jorge Royan, Wikimedia Commons // CC BY-SA 3.0

No one goes to Disneyland or Disney World to spend the day waiting in line, but when a queue is well-designed, waiting can be part of the experience. Disney knows this better than anyone, and the parks' Imagineers have developed several tricks over the years to make long wait times as painless as possible.

According to Popular Science, hacking the layout of the line itself is a simple way to influence the rider's perspective. When a queue consists of 200 people zig-zagging around ropes in a large, open room, it's easy for waiting guests to feel overwhelmed. This design allows riders to see exactly how many people are in line in front of them—which isn't necessarily a good thing when the line is long.

Imagineers prevent this by keeping riders in the dark when they enter the queue. In Space Mountain, for example, walls are built around the twisting path, so riders have no idea how much farther they have to go until they're deeper into the building. This stops people from giving up when they first get in line.

Another example of deception ride designers use is the "Machiavellian twist." If you've ever been pleasantly surprised by a line that moved faster than you expected, that was intentional. The signs listing wait times at the beginning of ride queues purposefully inflate the numbers. That way, when a wait that was supposed to be 120 minutes goes by in 90, you feel like you have more time than you did before.

The final trick is something Disney parks are famous for: By incorporating the same level of production design found on the ride into the queue, Imagineers make waiting in line an engaging experience that has entertainment value of its own. The Tower of Terror queue in Disney World, which is modeled after a decrepit 1930s hotel lobby down to the cobwebs and the abandoned coffee cups, feels like it could be a movie set. Some ride lines even use special effects. While waiting to ride Star Wars: Ride of the Resistance in Galaxy's Edge, guests get to watch holograms and animatronics that set up the story of the ride. This strategy exploits the so-called dual-task paradigm, which makes the line feel as if it's going by faster by giving riders mental stimulation as they wait.

Tricky ride design is just one of Disney's secrets. Here are more behind-the-scenes facts about the beloved theme parks.

[h/t Popular Science]