Alcohol-Producing Gut Bacteria May Harm Livers—Even if You Don't Drink

itakdalee/iStock via Getty Images
itakdalee/iStock via Getty Images

Teetotalers might think their liver is safe from the damaging effects of alcohol consumption, but new research is hinting that even non-drinkers and light drinkers might have cause for concern. It turns out a type of gut bacteria is capable of producing alcohol—and enough of it to potentially cause some pretty serious health consequences, including liver disease.

A study led by Jing Yuan at the Capital Institute of Pediatrics in Beijing, China and published in the journal Cell Metabolism offers details. After evaluating a patient with auto-brewery syndrome (ABS), a rare condition brought on by consumption and fermentation of sugary foods that leaves a person with high blood alcohol levels, researchers made an intriguing discovery. Rather than finding fermenting yeast that may have led to the condition, the patient’s stool contained Klebsiella pneumonia, a common gut bacteria capable of producing alcohol. In this subject, K. pneumonia was producing significantly more alcohol than in healthy patients.

The patient also had nonalcoholic fatty liver disease (NAFLD), characterized by fatty deposits in the liver. While many cases of NAFLD are relatively benign, too much fat can become toxic. Examining 43 other subjects with NAFLD, scientists found that that K. pneumonia was both present and potent, pumping out more alcohol than normal in 60 percent of participants with NAFLD. In the control group, a surplus was found in only 6.25 percent.

To further observe a correlation, scientists fed the bacteria to healthy, germ-free mice, who began to see an increase in fat in their livers after only one month. While not conclusive proof that the bacteria prompts NAFLD, it will likely trigger additional research in humans.

It’s not yet known how K. pneumonia acts in concert with the bacterial profile of the gut or what might make someone carrying stronger strains of the bacteria. Luckily, K. pneumonia can be treated with antibiotics. That’s good news for people who might never touch a drink and still find themselves with a damaged liver.

[h/t Live Science]

This Innovative Cutting Board Takes the Mess Out of Meal Prep

There's no way any of these ingredients will end up on the floor.
There's no way any of these ingredients will end up on the floor.
TidyBoard, Kickstarter

Transferring food from the cutting board to the bowl—or scraps to the compost bin—can get a little messy, especially if you’re dealing with something that has a tendency to roll off the board, spill juice everywhere, or both (looking at you, cherry tomatoes).

The TidyBoard, available on Kickstarter, is a cutting board with attached containers that you can sweep your ingredients right into, taking the mess out of meal prep and saving you some counter space in the process. The board itself is 15 inches by 20 inches, and the container that fits in its empty slot is 14 inches long, 5.75 inches wide, and more than 4 inches deep. Two smaller containers fit inside the large one, making it easy to separate your ingredients.

Though the 4-pound board hangs off the edge of your counter, good old-fashioned physics will keep it from tipping off—as long as whatever you’re piling into the containers doesn’t exceed 9 pounds. It also comes with a second set of containers that work as strainers, so you can position the TidyBoard over the edge of your sink and drain excess water or juice from your ingredients as you go.

You can store food in the smaller containers, which have matching lids; and since they’re all made of BPA-free silicone, feel free to pop them in the microwave. (Remove the small stopper on top of the lid first for a built-in steaming hole.)

tidyboard storage containers
They also come in gray, if teal isn't your thing.
TidyBoard

Not only does the bamboo-made TidyBoard repel bacteria, it also won’t dull your knives or let strong odors seep into it. In short, it’s an opportunity to make cutting, cleaning, storing, and eating all easier, neater, and more efficient. Prices start at $79, and it’s expected to ship by October 2020—you can find out more details and order yours on Kickstarter.

This article contains affiliate links to products selected by our editors. Mental Floss may receive a commission for purchases made through these links.

How the Scientist Who Invented Ibuprofen Accidentally Discovered It Was Great for Hangovers

This man had too many dry martinis at a business lunch.
This man had too many dry martinis at a business lunch.
George Marks/Retrofile/Getty Images

When British pharmacologist Stewart Adams and his colleague John Nicholson began tinkering with various drug compounds in the 1950s, they were hoping to come up with a cure for rheumatoid arthritis—something with the anti-inflammatory effects of aspirin, but without the risk of allergic reaction or internal bleeding.

Though they never exactly cured rheumatoid arthritis, they did succeed in developing a nonsteroidal anti-inflammatory drug (NSAID) that greatly reduced pain of all kinds. In 1966, they patented their creation, which was first known as 2-(4-isobutylphenyl) propionic acid and later renamed ibuprofen. While originally approved as a prescription drug in the UK, it soon became clear ibuprofen was safer and more effective than other pain relievers. It eventually hit the market as an over-the-counter medication.

During that time, Adams conducted one last impromptu experiment with the drug, which took place far outside the lab and involved only a single participant: himself.

In 1971, Adams arrived in Moscow to speak at a pharmacology conference and spent the night before his scheduled appearance tossing back shots of vodka at a reception with the other attendees. When he awoke the next morning, he was greeted with a hammering headache. So, as Smithsonian.com reports, Adams tossed back 600 milligrams of ibuprofen.

“That was testing the drug in anger, if you like,” Adams told The Telegraph in 2007. “But I hoped it really could work magic.”

As anyone who has ever been in that situation can probably predict, the ibuprofen did work magic on Adams’s hangover. After that, according to The Washington Post, the pharmaceutical company Adams worked for began promoting the drug as a general painkiller, and people started to stumble upon its use as a miracle hangover cure.

“It's funny now,” Adams told The Telegraph. “But over the years so many people have told me that ibuprofen really works for them, and did I know it was so good for hangovers? Of course, I had to admit I did.”

[h/t Smithsonian.com]