Human Body Temperatures Are Dropping, and Science Might Know Why

dcdp/iStock via Getty Images
dcdp/iStock via Getty Images

In 1868, German physician Carl Reinhold August Wunderlich started to popularize what’s become the most recognizable number in all of medicine: 98.6°F or 37°C, which is thought to be the normal average human body temperature. Though his methods later came under scrutiny—Wunderlich stuck an enormous thermometer under the armpits of patients for 20 minutes, a less-than-accurate technique—this baseline has helped physicians identify fevers as well as abnormally low body temperatures, along with corresponding illnesses or diseases.

More than 150 years later, 98.6° may no longer be the standard. Humans seem to be getting cooler. Researchers at Stanford University School of Medicine, in a paper published in the journal eLife, compared three large datasets from different time periods: American Civil War records, a national health survey from the 1970s, and a Stanford database from 2007-2017. By comparing recorded body temperatures, the researchers founds that men are now averaging a temperature .58°C less than what's long been considered normal, while women are .32°C lower. On average, each has decreased roughly .03°C every decade since the 1860s.

What drove us to chill out? Scientists have a few theories. A number of advances in human comfort have been ushered in since the 1800s, including better hygiene and readily available food, which may have slowed our metabolic rate (temperature is an indication of that rate). Chronic inflammation, which also raises body temperature, has decreased with the advent of vaccines, antibiotics, and better healthcare. The researchers propose that, on average, our bodies are healthier and slightly less warm.

After all, the average life expectancy in Wunderlich’s era was just 38 years.

[h/t The Independent]

Wayfair’s Fourth of July Clearance Sale Takes Up to 60 Percent Off Grills and Outdoor Furniture

Wayfair/Weber
Wayfair/Weber

This Fourth of July, Wayfair is making sure you can turn your backyard into an oasis while keeping your bank account intact with a clearance sale that features savings of up to 60 percent on essentials like chairs, hammocks, games, and grills. Take a look at some of the highlights below.

Outdoor Furniture

Brisbane bench from Wayfair
Brisbane/Wayfair

- Jericho 9-Foot Market Umbrella $92 (Save 15 percent)
- Woodstock Patio Chairs (Set of Two) $310 (Save 54 percent)
- Brisbane Wooden Storage Bench $243 (Save 62 percent)
- Kordell Nine-Piece Rattan Sectional Seating Group with Cushions $1800 (Save 27 percent)
- Nelsonville 12-Piece Multiple Chairs Seating Group $1860 (Save 56 percent)
- Collingswood Three-Piece Seating Group with Cushions $410 (Save 33 percent)

Grills and Accessories

Dyna-Glo electric smoker.
Dyna-Glo/Wayfair

- Spirit® II E-310 Gas Grill $479 (Save 17 percent)
- Portable Three-Burner Propane Gas Grill $104 (Save 20 percent)
- Digital Bluetooth Electric Smoker $224 (Save 25 percent)
- Cuisinart Grilling Tool Set $38 (Save 5 percent)

Outdoor games

American flag cornhole game.
GoSports

- American Flag Cornhole Board $57 (Save 19 percent)
- Giant Four in a Row Game $30 (Save 6 percent)
- Giant Jenga Game $119 (Save 30 percent)

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How the Scientist Who Invented Ibuprofen Accidentally Discovered It Was Great for Hangovers

This man had too many dry martinis at a business lunch.
This man had too many dry martinis at a business lunch.
George Marks/Retrofile/Getty Images

When British pharmacologist Stewart Adams and his colleague John Nicholson began tinkering with various drug compounds in the 1950s, they were hoping to come up with a cure for rheumatoid arthritis—something with the anti-inflammatory effects of aspirin, but without the risk of allergic reaction or internal bleeding.

Though they never exactly cured rheumatoid arthritis, they did succeed in developing a nonsteroidal anti-inflammatory drug (NSAID) that greatly reduced pain of all kinds. In 1966, they patented their creation, which was first known as 2-(4-isobutylphenyl) propionic acid and later renamed ibuprofen. While originally approved as a prescription drug in the UK, it soon became clear ibuprofen was safer and more effective than other pain relievers. It eventually hit the market as an over-the-counter medication.

During that time, Adams conducted one last impromptu experiment with the drug, which took place far outside the lab and involved only a single participant: himself.

In 1971, Adams arrived in Moscow to speak at a pharmacology conference and spent the night before his scheduled appearance tossing back shots of vodka at a reception with the other attendees. When he awoke the next morning, he was greeted with a hammering headache. So, as Smithsonian.com reports, Adams tossed back 600 milligrams of ibuprofen.

“That was testing the drug in anger, if you like,” Adams told The Telegraph in 2007. “But I hoped it really could work magic.”

As anyone who has ever been in that situation can probably predict, the ibuprofen did work magic on Adams’s hangover. After that, according to The Washington Post, the pharmaceutical company Adams worked for began promoting the drug as a general painkiller, and people started to stumble upon its use as a miracle hangover cure.

“It's funny now,” Adams told The Telegraph. “But over the years so many people have told me that ibuprofen really works for them, and did I know it was so good for hangovers? Of course, I had to admit I did.”

[h/t Smithsonian.com]