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Cephalopods Evolve Differently From the Rest of Us, Study Finds

NOAA OKEANOS EXPLORER Program, Gulf of Mexico 2014 Expedition via Flickr Creative Commons // CC BY 2.0
NOAA OKEANOS EXPLORER Program, Gulf of Mexico 2014 Expedition via Flickr Creative Commons // CC BY 2.0 | NOAA OKEANOS EXPLORER Program, Gulf of Mexico 2014 Expedition via Flickr Creative Commons // CC BY 2.0

The octopus is an animal with a seemingly endless amount of weird and wonderful traits, all the way down to its DNA. A new report published in the journal Cell has revealed yet another bizarre facet of cephalopod biology: the way they update their genes.

Coeloid cephalopods (that’s octopuses, squid, and cuttlefish) have evolved some truly mind-boggling abilities, from Houdini-like escape to crafting makeshift hunting blinds. They lack the standard optical equipment for color vision, yet scientists believe they can see in color anyway. And where warming waters have weakened other species, cephalopods populations appear to be booming.

The original cephalopod ancestor did not have all these traits. Their unique gifts, like ours, are the result of millions of years of evolution.

Animal evolution works like this: the genetic code of every member of a species is almost identical, but not quite. Each individual has a few DNA mutations that make it unique. When those mutations are advantageous in the environment, their owners will survive, reproduce, and pass the mutated DNA down to the next generation.

We also make changes to our RNA, but these are so scarce—in humans, just a few dozen sites amid roughly 20,000 genes—that their influence is relatively small.

But our rubbery-armed friends have apparently turned this system on its head. Researchers reviewing coeloid genomes say the cephalopods have evolved mostly through small, fluid changes to their RNA, and that their DNA doesn’t look like it’s been updated much at all.

The scientists found that around 11,000 of a squid’s 20,000 genes code for mutable RNA. Octopuses and cuttlefish genetics showed similar ratios, especially in the genes associated with their super-amazing, super-complex nervous systems. Nautiluses, those simpletons of the cephalopod family, looked more like us.

Liscovitch-Brauer et al. 2017. Cell.

Neurobiologist Clifton Ragdale of the University of Chicago was unaffiliated with the research but has worked on cephalopod genetics in the past. Speaking with Scientific American, he said the animals’ bizarro evolution scheme essentially represents “an alternative engine for cephalopod evolution.”

Ragsdale noted that scientists use DNA changes, not RNA, when determining evolutionary history. “This may mean that our molecular clock estimates of when different cephalopod lineages arose and diverged might be too recent. The Nobel Prize–winning biologist Sydney Brenner once said that octopi were the first intelligent beings on Earth. This could prove he was right.”