12 Facts About Diabetes Mellitus

iStock/mthipsorn
iStock/mthipsorn

Thirty million Americans—about 9 percent of the country's population—are living with diabetes mellitus, or simply diabetes. This chronic condition is characterized by sustained high blood sugar levels. In many patients, symptoms can be managed with insulin injections and lifestyle changes, but in others, the complications can be deadly. Here's what you need to know about diabetes mellitus.

1. There are three types of diabetes.

In healthy people, the pancreas produces enough of the hormone insulin to metabolize sugars into glucose and move the glucose into cells, where it's used for energy.

But people with type 2 diabetes—the most common form of the disease, accounting for about 95 percent of cases—either can't produce enough insulin to transport the sugars, or their cells have become insulin-resistant. The result is a buildup of glucose in the blood (a.k.a. high blood sugar or hyperglycemia). Type 2 diabetes typically develops in adults.

Type 1 diabetes, also known as juvenile diabetes, makes up the remaining 5 percent of chronic cases and most often develops in children and young adults. With this condition, the initial problem isn’t blood sugar levels, but insulin production: The pancreas can’t make enough insulin to process even normal amounts of glucose. The sugar builds up as a result, leading to dangerous concentrations in the bloodstream.

The third form, gestational diabetes, only afflicts pregnant people who weren’t diabetic before their pregnancy. The mother's blood glucose levels usually spike around the 24th week of pregnancy, but with a healthy diet, exercise, and insulin shots in some cases, diabetes symptoms usually can be managed. Blood sugar levels tend to return to normal in patients following their pregnancies.

2. The mellitus in diabetes mellitus means "honey sweet."

Around 3000 years ago, ancient Egyptians described a condition with diabetes-like symptoms, though it wasn't called diabetes yet. It took a few hundred years before the Greek physician Araetus of Cappodocia came up with the name diabetes based on the Greek word for "passing through" (as in passing a lot of urine, a common diabetes symptom). English doctor Thomas Willis tacked on the word mellitus, meaning "honey sweet," in 1675, building on previous physicians' observations that diabetic patients had sweet urine. Finally, in 1776, another English physician named Matthew Dobson confirmed that both the blood and urine of diabetes patients were made sweeter by high levels of glucose in their blood.

3. The cause of one type of diabetes is well understood; the other, not so much.

A person’s lifestyle is a key predictor of developing type 2 diabetes. Factors like being overweight or obese, consuming a high-calorie diet, smoking, and seldom exercising contribute to the risk. Foods and drinks that are high in sugar—soda, candy, ice cream, dessert— may contribute to hyperglycemia, but any food that’s high in calories, even if it's not sweet, can raise blood sugar levels.

In contrast to these well-established factors, medical experts aren’t entirely sure what causes type 1 diabetes. We do know that type 1 is an autoimmune disease that develops when the body attacks and damages insulin-producing cells in the pancreas. Some scientists think that environmental factors, like viruses, may trigger this immune response.

4. Family history also plays a role in diabetes risk.

If a parent or sibling has type 2 diabetes, you are predisposed to developing pre-diabetes and type 2 diabetes. Lifestyle habits explain some of these incidences, since family members may share similar diets and exercise habits. Genetics also play a role, but just because one close relative has diabetes does not mean you're destined to. Research conducted on identical twins, which share identical genes, showed that the pairs have discordant risk. Among twins in which one has type 1 diabetes, the other has only a 50 percent chance of developing it; for type 2, the risk for the second twin is 75 percent at most.

5. Racial minorities are at a higher risk for developing diabetes.

Many racial minority groups in the U.S. have a higher chance of developing type 2 diabetes. Black Americans, Latino Americans, Native Americans, Pacific Islanders, and some groups of Asian Americans are more likely to have pre-diabetes and type 2 diabetes than white Americans. This can be partly explained by the fact that some of these groups also have higher rates of obesity, which is one of the primary risk factors of type 2 diabetes. Socioeconomics may also play a role: One study shows that people with diabetes living in poverty are less likely to visit diabetes clinics and receive proper testing than their middle-income counterparts. According to another study, diabetic people without health insurance have higher blood sugar, blood pressure, and cholesterol rates than insured diabetics. Genetics, on the other hand, don’t appear to contribute to these trends.

6. Diabetes is one of the world's deadliest diseases.

With proper management, people with diabetes can live long, comfortable lives. But if the disease isn’t treated, it can have dire consequences. Diabetics make up the majority of people who develop chronic kidney disease, have adult-onset blindness, and need lower-limb amputations. In the most serious cases, diabetes leads to death. The condition is one of the deadliest diseases in the world, killing more people than breast cancer and AIDS combined.

7. Millions of Americans are pre-diabetic.

According to the CDC, 84 million adults living in the U.S. are pre-diabetic: Their blood sugar is higher than what’s considered safe, but hasn't yet reached diabetic level. In pre-diabetic patients, blood glucose levels after eight hours of fasting fall between 100 and 125 milligrams per deciliter, and diabetic levels are anything above that. People with pre-diabetes are not just at a greater risk for type 2 diabetes, but also for heart disease and stroke. Fortunately, people who are diagnosed with pre-diabetes can take steps to eat a healthier diet, increase physical activity, and test their blood glucose level several times a day to control the condition. In some cases, doctors will prescribe drugs like metformin that make the body more receptive to the insulin it produces.

8. After climbing for decades, rates of diabetes incidence are declining.

In the U.S., the rate of new diagnoses skyrocketed 382 percent between 1988 and 2014. Globally, 108 million people had diabetes in 1980, but by 2014 that number was 422 million.

But thanks to nationwide education and prevention efforts, the trend has reversed in the U.S., according to the CDC. Since peaking in 2009, the number of new diabetes cases in America has dropped by 35 percent. In that same timeframe, the number of people living with diagnosed diabetes in the U.S. has plateaued, suggesting people with the condition are living longer.

9. The first successful treatment for type 1 diabetes occurred in 1922.

Prior to the 20th century, type 1 diabetes was usually fatal. Diabetic ketoacidosis—a toxic buildup of chemicals called ketones, which arise when the body can no longer use glucose and instead breaks down other tissues for energy—killed most patients within a year or two of diagnosis. In searching for way to save children with juvenile (type 1) diabetes, Canadian physician Frederick Banting and medical student Charles Best built on the work of earlier researchers, who had demonstrated that removing the pancreas from a dog immediately caused diabetes symptoms in the animal. Banting and Best extracted insulin from dog pancreases in University of Toronto professor J.J.R. Macleod's lab. After injecting the insulin back into dogs whose pancreases had been removed, they realized the hormone regulated blood sugar levels. On January 11, 1922, they administered insulin to a human patient, and further refined the extract to reduce side effects. In 1923, Banting and Macleod received the Nobel Prize in Medicine for their work.

10. A pioneering physicist discovered the difference between type and and type 1 diabetes.

In the 1950s, physicist Rosalyn Yalow and her research partner Solomon Berson developed a method for measuring minute amounts of substances in blood. Inspired by Yalow's husband's struggle with diabetes, Yalow focused her research on insulin. Their "radioimmunoassay" technology revealed that some diabetes patients were still able to produce their own insulin, leading them to create two separate categories for the disease: “insulin-dependent” (type 1) and “non-insulin-dependent” (type 2). Prior to that discovery in 1959, there was no distinction between the two types. In 1977, Yalow won the 1977 Nobel Prize in Medicine for the radioimmunoassay, one of only 12 female Nobel laureates in medicine.

11. Making one insulin dose once required tons of pig parts.

Insulin is relatively easy to make today. Most of what's used in injections comes from a special non-disease-producing laboratory strain of E. coli bacteria that's been genetically modified to produce insulin, but that wasn't always the case. Until about 40 years ago, 2 tons of pig pancreases were required to produce just 8 ounces of pure insulin. The pig parts were typically recycled from pork farms.

12. A quarter of diabetes patients don’t know they have it.

The symptoms of type 2 diabetes can develop for years before patients think to ask their doctor about them. These include frequent urination, unexplained thirst, numbness in the extremities, dry skin, blurry vision, fatigue, and sores that are slow to heal—signs that may not be a cause for concern on their own, but together can indicate a more serious problem. Patients with type 1 diabetes may also experience nausea, vomiting, and stomach pain.

While serious, the symptoms of diabetes are sometimes easy to overlook. That’s why 25 percent of people with the illness, 7.2 million in the U.S., are undiagnosed. And that number doesn’t even cover the majority of people with pre-diabetes who aren’t aware they’re on their way to becoming diabetic.

Veterans Can Now Access Their Health Records Through Apple’s Health App

SeventyFour/iStock via Getty Images
SeventyFour/iStock via Getty Images

Apple’s iOS Health app is great for more than just checking how many steps you took during a lengthy walk in the park—it also stores health records from Johns Hopkins, Quest Diagnostics, Allscripts, and more than 400 other healthcare organizations.

Now, Fortune reports that the U.S. Department of Veterans Affairs (VA) has joined that list, making it easier than ever for military veterans who receive healthcare through the Veterans Health Administration to access all of their health records, including medications, immunizations, lab results, and other information. In the press release, Apple explains that the app will automatically update the records, so all veterans need to do is log into their providers’s patient portals through the Health app for a “single, integrated snapshot of their health profile whenever they want, quickly, and privately.”

apple VA health app screenshot
Apple

Though the official announcement coincides nicely with Veterans Day on Monday, the change itself has been in the works for several months—the VA released the new feature to certain patients over the summer.

According to its website, the Veterans Health Administration is the largest integrated healthcare system in the country, servicing more than 9 million patients across 1255 healthcare facilities. With such an expansive network, any successful attempt to streamline processes and improve the flow of information—especially when it comes to sensitive, personal data—has the potential to be a major game-changer for veterans.

apple VA health app screenshot
Apple

“Helping veterans gain a better understanding of their health is our chance to show our gratitude for their service,” Apple COO Jeff Williams said in the press release. “By working with the VA to offer Health Records on iPhone, we hope to help those who served have greater peace of mind that their healthcare is in good hands.”

Wondering what you can do to help veterans? Here are 11 honorable ideas.

[h/t Fortune]

A Handful of Lucky College Students Live With Senior Citizens in This Minnesota Mansion

vadimguzhva/iStock via Getty Images
vadimguzhva/iStock via Getty Images

When Winona State University student Ashley McGaw skateboards home after a long day of nursing classes, she’s greeted by an unusual entourage: the elderly residents of a Minnesota assisted living facility called Senior Living at Watkins.

According to WFAA, McGaw and several other college kids live there with 45 seniors as part of Winona Health’s “Students in Residence" program, in which students volunteer their time with residents in exchange for discounted rent. For 10 volunteer hours per month, it’s $400, and doubling your hours drops it to just $200 per month. Not only does that include meals, it also gives students the chance to forgo the usual college dorm building for the stately glamour of an old mansion—their rooms are located in the historic Watkins Manor House, which is attached to the assisted living facility.

For freshman Joel Olson, the opportunity seemed like a no-brainer.

“'All you have to do is spend some time with some really nice people?'” he remembers thinking, according to KARE 11. “Of course!”

As for how they spend that time, it’s up to the students. Graduate student Laura Jensen hosts weekly crocheting sessions, nursing student Hanna Rottier offers manicures, and bulletin boards advertise free tech support.

And, in return for sharing their time and talents, students get to experience the familial affection and grandparental concern that’s often scarce on a college campus.

“They all mother me,” Jensen tells KARE 11 about the members of her crocheting club. “They take care of me.”

Winona Health assisted living director Cheryl Krage sees evidence of this, too.

“I hear residents wondering how the students are doing with their studies,” Winona Health assisted living director Cheryl Krage tells KARE 11. “‘Are you eating enough, are you getting enough fruits and vegetable[s]?"

According to the program page on Winona Health’s website, the program is especially beneficial to students looking to enter the healthcare industry, whether that’s medical school, nursing, social work, rehabilitative therapy, or even music therapy.

It also keeps senior citizens connected to the next generation in a deeper way.

“Helps us stay young – ger,” senior resident Diane Sheldon told KARE 11.

[h/t WFAA]

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